Updated on 2025/07/07

写真a

 
DAN Ippeita
 
Organization
Faculty of Science and Engineering Professor
Other responsible organization
Civil, Human and Environmental Science and Engineering Course of Graduate School of Science and Engineering, Master's Program
Civil, Human and Environmental Science and Engineering Course of Graduate School of Science and Engineering, Doctoral Program
Contact information
The inquiry by e-mail is 《here》
Homepage
http://brain-lab.jp
External link

Degree

  • 博士（学術） ( 東京大学 )

  • 学術修士 ( 東京大学 )

Education

  • 1999.3
     

    The University of Tokyo   Graduate School, of Arts and Sciences   doctor course   finished without a degree

  • 1996.3
     

    The University of Tokyo   Graduate School, of Arts and Sciences   master course   completed

  • 1993.3
     

    International Christian University   Faculty of Liberal Arts   graduated

  • 1992.9
     

    University of Illinois at Urbana-Champaign   Liberal Arts College   others

  • 1988.3
     

    東京都立富士高等学校   graduated

Research History

  • 2025.3 - Now

    中央大学情報農学部（仮称）開設準備室副室長

  • 2013.4 - Now

    Chuo University   Faculty of Science and Engineering   Professor

  • 2022.4 - 2024.3

    日本女子大学文理学部心理学科   非常勤講師

  • 2013.4 - 　

    獨協医科大学医学部神経内科学講座 非常勤講師

  • 2013.4 - 　

    自治医科大学医学部先端医療技術開発センター脳機能研究部門 非常勤講師

  • 2010.4 - 2013.3

    Jichi Medical University School of Medicine   Associate Professor

  • 2010.4 - 2011.3

    東京医科歯科大学歯学部 非常勤講師

  • 2008.2 - 2010.3

    独立行政法人農業・食品産業技術研究機構食品総合研究所 主任研究員

  • 2008.2 - 2010.3

    National Food Research Institute   Cognitive Food Science Unit   Senior Researcher

  • 2008.12 　 　

    筑波大学大学院人間総合科学研究科感性認知脳科学専攻 非常勤講師

  • 2006.4 - 2008.1

    独立行政法人農業・食品産業技術研究機構食品総合研究所 研究員

  • 2005.2 - 2006.3

    独立行政法人食品総合研究所 研究員

  • 2002.4 - 2005.1

    独立行政法人食品総合研究所重点領域 特別研究員

  • 2001.4 - 2002.3

    科学技術振興事業団CREST松本邦弘チーム 研究員

  • 2000.12 - 2001.3

    科学技術振興事業団CREST松本邦弘チーム 非常勤職員

  • 2000.7 - 2000.11

    株式会社応微研 研究員 兼 営業部テクニカルコンサルタント

  • 1999.4 - 2000.6

    科学技術振興事業団ERATO楠見膜組織能プロジェクト 研究員

  • 1996.4 - 1999.3

    日本学術振興会 特別研究員DC1

  • 1997.9 - 1998.3

    国際基督教大学教養学部理学科 非常勤講師

  • 1996.12 - 1997.3

    国際基督教大学教養学部理学科 非常勤講師

  • 1993.4 - 1994.3

    国立衛生試験所化学物質情報部 非常勤職員

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Professional Memberships

  • 日本光脳機能イメージング学会

  • Society for fNIRS

  • 日本生理心理学会

  • 日本感性工学会

  • 日本神経科学会

  • 日本ヒト脳機能マッピング学会

  • 日本心理学会

  • 日本社会心理学会

  • 日本薬物脳波学会

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Research Interests

  • fNIRS

  • 脳

  • 応用認知脳科学

  • 心理統計学 食

  • Consumer Neuroscience

  • Neuromarketing

  • Psychophysiology

Research Areas

  • Humanities & Social Sciences / Social psychology

  • Humanities & Social Sciences / Family and consumer sciences, and culture and living

  • Life Science / Medical systems

  • Life Science / Neuroscience-general

  • Humanities & Social Sciences / Cognitive science

Papers

  • Adjusting effective multiplicity ( M eff ) for family-wise error rate in functional near-infrared spectroscopy data with a small sample size. Reviewed International journal

    Yuki Yamamoto, Wakana Kawai, Tatsuya Hayashi, Minako Uga, Yasushi Kyutoku, Ippeita Dan

    Neurophotonics   11 ( 3 )   035004 - 035004   2024.7

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    Authorship：Last author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    SIGNIFICANCE: The advancement of multichannel functional near-infrared spectroscopy (fNIRS) has enabled measurements across a wide range of brain regions. This increase in multiplicity necessitates the control of family-wise errors in statistical hypothesis testing. To address this issue, the effective multiplicity ( M eff ) method designed for channel-wise analysis, which considers the correlation between fNIRS channels, was developed. However, this method loses reliability when the sample size is smaller than the number of channels, leading to a rank deficiency in the eigenvalues of the correlation matrix and hindering the accuracy of M eff calculations. AIM: We aimed to reevaluate the effectiveness of the M eff method for fNIRS data with a small sample size. APPROACH: In experiment 1, we used resampling simulations to explore the relationship between sample size and M eff values. Based on these results, experiment 2 employed a typical exponential model to investigate whether valid M eff could be predicted from a small sample size. RESULTS: Experiment 1 revealed that the M eff values were underestimated when the sample size was smaller than the number of channels. However, an exponential pattern was observed. Subsequently, in experiment 2, we found that valid M eff values can be derived from sample sizes of 30 to 40 in datasets with 44 and 52 channels using a typical exponential model. CONCLUSIONS: The findings from these two experiments indicate the potential for the effective application of M eff correction in fNIRS studies with sample sizes smaller than the number of channels.

    DOI： 10.1117/1.NPh.11.3.035004

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  • Visual Recognizability Evaluation for Brand Logos Using Covert Eye Tracking (CovET) Combined with a Go/No-go Task Reviewed

    Otoha YAMANAKA, Rina NIBE, Kenta NAKAZAWA, Yuki YAMAMOTO, Wakana KAWAI, Yasushi KYUTOKU, Ippeita DAN

    International Journal of Affective Engineering   2024

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    DOI： 10.5057/ijae.ijae-d-24-00019

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  • Extracting Facilitators of New Businesses Within an Existing Company Using Textual Data Generated from Structured Descriptive Questions Based on a Two-dimensional Framework Reviewed

    TAKI Shoi, DAN Ippeita, MINAMI Yuko, HANDA Toru, KYUTOKU Yasushi

    International Journal of Affective Engineering   23 ( 2 )   143 - 155   2024

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    Authorship：Corresponding author   Language：English   Publisher：Japan Society of Kansei Engineering  

    New businesses created within an existing company are important for corporate sustainability. We explored facilitators of new businesses within a company by analyzing text data. We first extracted definitions of new businesses, then developed a two-dimensional framework based on Motivation-Hygiene and Job Demands-Resources to extract factors from a limited sample. Five descriptive questions including four structured questions based on the framework were answered by 100 anonymous participants involved in new businesses within a company. We conducted co-occurrence analyses on the data obtained and defined new businesses within a company as “A service or product for expanding profits in an area slightly different from the existing model.” Eight factors facilitating or hindering new businesses within a company were identified. This approach reduces feedback bias and ensures ease of analysis and validity of the results. This method of using the framework is expected to be effective in other fields.

    DOI： 10.5057/ijae.ijae-d-23-00045

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  • Visualizing the IKEA effect: experiential consumption assessed with fNIRS-based neuroimaging Reviewed

    Hiroki Oishi, Kenta Nakazawa, Tomoki Takahashi, Yasushi Kyutoku, Ippeita Dan

    Frontiers in Neuroergonomics   2023.4

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    <jats:sec><jats:title>Introduction</jats:title><jats:p>In recent years, experiential consumption, which refers to purchases involving hedonic experiences, has been gathering attention in marketing research. Experiential consumption is closely related to cognitive biases, and among them, we focus on the IKEA effect, which is a cognitive bias in which the maximum willingness to pay (WTP) for a product is high because the experience of assembling the product is highly valued. Since no studies have examined the neural mechanism behind the IKEA effect, here we present the first study exploring the neural substrates of the IKEA effect using functional near-infrared spectroscopy (fNIRS). During the WTP evaluation, we expect the attachment to and memory retrieval of DIY products to be the cognitive mechanism for the IKEA effect.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>Thirty healthy students, of which 24 were confirmed to have undergone the IKEA effect, were asked to perform a WTP evaluation task after assembling three types of do-it-yourself (DIY) products and handling three types of Non-DIY products. Their cerebral hemodynamic responses during the evaluation were measured using fNIRS. In order to adjust for temporal variability of cortical responses among participants, a personalized adaptive general linear model (GLM) analysis was adopted. Then, one-sample <jats:italic>t</jats:italic>-tests were performed for each DIY and Non-DIY condition for the obtained β values, and a paired <jats:italic>t</jats:italic>-test was performed between DIY and Non-DIY conditions.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>We identified brain regions, including the left-inferior frontal gyrus (L-IFG) and left-middle frontal gyrus (L-MFG), which were probably related to cognitive processing related to the IKEA effect. Among them, the L-MFG exhibited more activation during the DIY condition than during the Non-DIY condition.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>To our knowledge, the current study is the first to reveal the neural basis of the IKEA effect. The cortical activation during evaluation of WTP for DIY and Non-DIY products exhibited marked differences. In addition to the R-IFG activation often reported for WTP evaluations, we revealed that other regions, in particular the L-IFG and L-MFG, were activated during the DIY condition. These areas are considered to be related to memory and attachment, which would serve as reasonable cognitive constituents for the IKEA effect. In conclusion, this study suggests that the value of experiential consumption can be assessed using fNIRS-based neuroimaging and provides a novel approach to consumer neuroergonomics. It is predicted that visualization the value of experiential consumption will create marketing opportunities for more and more companies and the visualization will become an indispensable method in the future.</jats:p></jats:sec>

    DOI： 10.3389/fnrgo.2023.1129582

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  • Best practices for fNIRS publications. Reviewed International journal

    Meryem A Yücel, Alexander V Lühmann, Felix Scholkmann, Judit Gervain, Ippeita Dan, Hasan Ayaz, David Boas, Robert J Cooper, Joseph Culver, Clare E Elwell, Adam Eggebrecht, Maria A Franceschini, Christophe Grova, Fumitaka Homae, Frédéric Lesage, Hellmuth Obrig, Ilias Tachtsidis, Sungho Tak, Yunjie Tong, Alessandro Torricelli, Heidrun Wabnitz, Martin Wolf

    Neurophotonics   8 ( 1 )   012101 - 012101   2021.1

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

    The application of functional near-infrared spectroscopy (fNIRS) in the neurosciences has been expanding over the last 40 years. Today, it is addressing a wide range of applications within different populations and utilizes a great variety of experimental paradigms. With the rapid growth and the diversification of research methods, some inconsistencies are appearing in the way in which methods are presented, which can make the interpretation and replication of studies unnecessarily challenging. The Society for Functional Near-Infrared Spectroscopy has thus been motivated to organize a representative (but not exhaustive) group of leaders in the field to build a consensus on the best practices for describing the methods utilized in fNIRS studies. Our paper has been designed to provide guidelines to help enhance the reliability, repeatability, and traceability of reported fNIRS studies and encourage best practices throughout the community. A checklist is provided to guide authors in the preparation of their manuscripts and to assist reviewers when evaluating fNIRS papers.

    DOI： 10.1117/1.NPh.8.1.012101

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  • Language Familiarity and Proficiency Leads to Differential Cortical Processing During Translation Between Distantly Related Languages. Reviewed International journal

    Katsumasa Shinozuka, Kiyomitsu Niioka, Tatsuya Tokuda, Yasushi Kyutoku, Koki Okuno, Tomoki Takahashi, Ippeita Dan

    Frontiers in human neuroscience   15   593108 - 593108   2021

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    In the midst of globalization, English is regarded as an international language, or Lingua Franca, but learning it as a second language (L2) remains still difficult to speakers of other languages. This is true especially for the speakers of languages distantly related to English such as Japanese. In this sense, exploring neural basis for translation between the first language (L1) and L2 is of great interest. There have been relatively many previous researches revealing brain activation patterns during translations between L1 and English as L2. These studies, which focused on language translation with close or moderate linguistic distance (LD), have suggested that the Broca area (BA 44/45) and the dorsolateral prefrontal cortex (DLPFC; BA 46) may play an important role on translation. However, the neural mechanism of language translation between Japanese and English, having large LD, has not been clarified. Thus, we used functional near infrared spectroscopy (fNIRS) to investigate the brain activation patterns during word translation between Japanese and English. We also assessed the effects of translation directions and word familiarity. All participants' first language was Japanese and they were learning English. Their English proficiency was advanced or elementary. We selected English and Japanese words as stimuli based on the familiarity for Japanese people. Our results showed that the brain activation patterns during word translation largely differed depending on their English proficiency. The advanced group elicited greater activation on the left prefrontal cortex around the Broca's area while translating words with low familiarity, but no activation was observed while translating words with high familiarity. On the other hand, the elementary group evoked greater activation on the left temporal area including the superior temporal gyrus (STG) irrespective of the word familiarity. These results suggested that different cognitive process could be involved in word translation corresponding to English proficiency in Japanese learners of English. These difference on the brain activation patterns between the advanced and elementary group may reflect the difference on the cognitive loads depending on the levels of automatization in one's language processing.

    DOI： 10.3389/fnhum.2021.593108

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  • Willingness-to-Pay-Associated Right Prefrontal Activation During a Single, Real Use of Cosmetics as Revealed by Functional Near-Infrared Spectroscopy Reviewed International journal

    Keith Kawabata Duncan, Tatsuya Tokuda, Chiho Sato, Keiko Tagai, Ippeita Dan

    FRONTIERS IN HUMAN NEUROSCIENCE   13   16 - 16   2019.2

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    DOI： 10.3389/fnhum.2019.00016

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  • Individual classification of ADHD children by right prefrontal hemodynamic responses during a go/no-go task as assessed by fNIRS Reviewed International journal

    Yukifumi Monden, Ippeita Dan, Masako Nagashima, Haruka Dan, Minako Uga, Takahiro Ikeda, Daisuke Tsuzuki, Yasushi Kyutoku, Yuji Gunji, Daisuke Hirano, Takamichi Taniguchi, Hideo Shimoizumi, Eiju Watanabe, Takanori Yamagata

    NEUROIMAGE-CLINICAL   9   1 - 12   2015

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    DOI： 10.1016/j.nicl.2015.06.011

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  • Neuropharmacological effect of atomoxetine on attention network in children with attention deficit hyperactivity disorder during oddball paradigms as assessed using functional near-infrared spectroscopy Reviewed International journal

    Masako Nagashima, Yukifumi Monden, Ippeita Dan, Haruka Dan, Tsutomu Mizutani, Daisuke Tsuzuki, Yasushi Kyutoku, Yuji Gunji, Daisuke Hirano, Takamichi Taniguchi, Hideo Shimoizumi, Mariko Y. Momoi, Takanori Yamagata, Eiju Watanabe

    NEUROPHOTONICS   1 ( 2 )   025007 - 025007   2014.10

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    DOI： 10.1117/1.NPh.1.2.025007

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  • Optimizing the general linear model for functional near-infrared spectroscopy: an adaptive hemodynamic response function approach Reviewed International journal

    Minako Uga, Ippeita Dan, Toshifumi Sano, Haruka Dan, Eiju Watanabe

    NEUROPHOTONICS   1 ( 1 )   015004 - 015004   2014.7

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    Authorship：Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1117/1.NPh.1.1.015004

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  • Neuropharmacological effect of methylphenidate on attention network in children with attention deficit hyperactivity disorder during oddball paradigms as assessed using functional near-infrared spectroscopy Reviewed International journal

    Masako Nagashima, Yukifumi Monden, Ippeita Dan, Haruka Dan, Daisuke Tsuzuki, Tsutomu Mizutani, Yasushi Kyutoku, Yuji Gunji, Mariko Y. Momoi, Eiju Watanabe, Takanori Yamagata

    NEUROPHOTONICS   1 ( 1 )   015001 - 015001   2014.7

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    Authorship：Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1117/1.NPh.1.1.015001

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  • Spatial registration for functional near-infrared spectroscopy: From channel position on the scalp to cortical location in individual and group analyses Reviewed International journal

    Daisuke Tsuzuki, Ippeita Dan

    NEUROIMAGE   85   92 - 103   2014.1

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    Authorship：Last author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.neuroimage.2013.07.025

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  • Acute neuropharmacological effects of atomoxetine on inhibitory control in ADHD children: A fNIRS study Reviewed International journal

    Masako Nagashima, Yukifumi Monden, Ippeita Dan, Haruka Dan, Daisuke Tsuzuki, Tsutomu Mizutani, Yasushi Kyutoku, Yuji Gunji, Daisuke Hirano, Takamichi Taniguchi, Hideo Shimoizumi, Mariko Y. Momoi, Eiju Watanabe, Takanori Yamagata

    NEUROIMAGE-CLINICAL   6   192 - 201   2014

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.nicl.2014.09.001

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  • Cognitive and Psychological Reactions of the General Population Three Months After the 2011 Tohoku Earthquake and Tsunami Reviewed International journal

    Yasushi Kyutoku, Ryoko Tada, Takahiko Umeyama, Kenji Harada, Senichiro Kikuchi, Eiju Watanabe, Angela Liegey-Dougall, Ippeita Dan

    PLOS ONE   7 ( 2 )   e31014   2012.2

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    DOI： 10.1371/journal.pone.0031014

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  • Right prefrontal activation as a neuro-functional biomarker for monitoring acute effects of methylphenidate in ADHD children: An fNIRS study Reviewed International journal

    Yukifumi Monden, Haruka Dan, Masako Nagashima, Ippeita Dan, Daisuke Tsuzuki, Yasushi Kyutoku, Yuji Gunji, Takanori Yamagata, Eiju Watanabe, Mariko Y. Momoi

    NEUROIMAGE-CLINICAL   1 ( 1 )   131 - 140   2012

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    Authorship：Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.nicl.2012.10.001

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  • Virtual spatial registration of stand-alone MRS data to MNI space Reviewed International journal

    Daisuke Tsuzuki, Valer Jurcak, Archana K. Singh, Masako Okamoto, Eiju Watanabe, Ippeita Dan

    NEUROIMAGE   34 ( 4 )   1506 - 1518   2007.2

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    DOI： 10.1016/j.neuroimage.2006.10.043

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  • 10/20, 10/10, and 10/5 systems revisited: Their validity as relative head-surface-based positioning systems Reviewed International journal

    Valer Jurcak, Daisuke Tsuzuki, Ippeita Dan

    NEUROIMAGE   34 ( 4 )   1600 - 1611   2007.2

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    DOI： 10.1016/j.neuroimage.2006.09.024

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  • Spatial registration of multichannel multi-subject fNIRS data to MNI space without MRI. Reviewed International journal

    Archana K Singh, Masako Okamoto, Haruka Dan, Valer Jurcak, Ippeita Dan

    NeuroImage   27 ( 4 )   842 - 51   2005.10

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    Authorship：Last author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    The registration of functional brain data to the common brain space offers great advantages for inter-modal data integration and sharing. However, this is difficult to achieve in functional near-infrared spectroscopy (fNIRS) because fNIRS data are primary obtained from the head surface and lack structural information of the measured brain. Therefore, in our previous articles, we presented a method for probabilistic registration of fNIRS data to the standard Montreal Neurological Institute (MNI) template through international 10-20 system without using the subject's magnetic resonance image (MRI). In the current study, we demonstrate our method with a new statistical model to facilitate group studies and provide information on different components of variability. We adopt an analysis similar to the single-factor one-way classification analysis of variance based on random effects model to examine the variability involved in our improvised method of probabilistic registration of fNIRS data. We tested this method by registering head surface data of twelve subjects to seventeen reference MRI data sets and found that the standard deviation in probabilistic registration thus performed for given head surface points is approximately within the range of 4.7 to 7.0 mm. This means that, if the spatial registration error is within an acceptable tolerance limit, it is possible to perform multi-subject fNIRS analysis to make inference at the population level and to provide information on positional variability in the population, even when subjects' MRIs are not available. In essence, the current method enables the multi-subject fNIRS data to be presented in the MNI space with clear description of associated positional variability. Such data presentation on a common platform, will not only strengthen the validity of the population analysis of fNIRS studies, but will also facilitate both intra- and inter-modal data sharing among the neuroimaging community.

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  • Three-dimensional probabilistic anatomical cranio-cerebral correlation via the international 10-20 system oriented for transcranial functional brain mapping. Reviewed International journal

    Masako Okamoto, Haruka Dan, Kuniko Sakamoto, Kazuhiro Takeo, Koji Shimizu, Satoru Kohno, Ichiro Oda, Seiichiro Isobe, Tateo Suzuki, Kaoru Kohyama, Ippeita Dan

    NeuroImage   21 ( 1 )   99 - 111   2004.1

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    Authorship：Last author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    The recent advent of multichannel near-infrared spectroscopy (NIRS) has expanded its technical potential for human brain mapping. However, NIRS measurement has a technical drawback in that it measures cortical activities from the head surface without anatomical information of the object to be measured. This problem is also found in transcranial magnetic stimulation (TMS) that transcranially activates or inactivates the cortical surface. To overcome this drawback, we examined cranio-cerebral correlation using magnetic resonance imaging (MRI) via the guidance of the international 10-20 system for electrode placement, which had originally been developed for electroencephalography. We projected the 10-20 standard cranial positions over the cerebral cortical surface. After examining the cranio-cerebral correspondence for 17 healthy adults, we normalized the 10-20 cortical projection points of the subjects to the standard Montreal Neurological Institute (MNI) and Talairach stereotactic coordinates and obtained their probabilistic distributions. We also expressed the anatomical structures for the 10-20 cortical projection points probabilistically. Next, we examined the distance between the cortical surface and the head surface along the scalp and created a cortical surface depth map. We found that the locations of 10-20 cortical projection points in the standard MNI or Talairach space could be estimated with an average standard deviation of 8 mm. This study provided an initial step toward establishing a three-dimensional probabilistic anatomical platform that enables intra- and intermodal comparisons of NIRS and TMS brain imaging data.

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  • The Ste20 group kinases as regulators of MAP kinase cascades Reviewed

    Ippeita Dan, Norinobu M. Watanabe, Akihiro Kusumi

    Trends in Cell Biology   11 ( 5 )   220 - 230   2001.5

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    DOI： 10.1016/S0962-8924(01)01980-8

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  • Psychological Factors that Influence Behavioral Intentions towards Bottled Green Tea in the Japanese Market Reviewed

    Christopher DEMETRAKOS, Itsuki NAKATO, Shannen ROMERO-PEREZ, Yasushi KYUTOKU, Ippeita DAN

    International Journal of Affective Engineering   24 ( 1 )   103 - 114   2025

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    Authorship：Last author,　Corresponding author   Publishing type：Research paper (scientific journal)   Publisher：Japan Society of Kansei Engineering  

    DOI： 10.5057/ijae.ijae-d-24-00013

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  • Deconstructing the Psychological Factors behind Brand Perceptions of Bottled Japanese Green Tea in Competitive Japanese Market Reviewed

    Christopher DEMETRAKOS, Itsuki NAKATO, Shannen ROMERO-PEREZ, Yasushi KYUTOKU, Ippeita DAN

    International Journal of Affective Engineering   24 ( 1 )   115 - 127   2025

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    Authorship：Last author,　Corresponding author   Publishing type：Research paper (scientific journal)   Publisher：Japan Society of Kansei Engineering  

    DOI： 10.5057/ijae.ijae-d-24-00016

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  • Visualizing changes in cerebral hemodynamics in children with ADHD who have discontinued methylphenidate: A pilot study on using brain function for medication discontinuation decisions. Reviewed International journal

    Koyuru Kurane, Niannian Lin, Ippeita Dan, Hikari Tanaka, Yuki Tsuji, Wakana Ito, Shiho Yanagida, Yukifumi Monden

    Brain & development   2024.10

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    Authorship：Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    OBJECTIVE: This study undertook neuropharmacological research on the clinical course of controlled medication discontinuation to guide practitioners who are considering stopping medications for youths with attention-deficit hyperactivity disorder (ADHD). METHODS: This study analyzed the data for 14 ADHD children (12 male and 2 female) in two datasets: The children prescribed methylphenidate (MPH) were at an initial mean age of 7.5 years (SD = 1.70, range: 6-11) with a mean ADHD-Rating Score (ADHD-RS) of 26.6 (SD = 8.64, range 15-40). The children who discontinued MPH based on clinical judgment were at a mean age of 12.21 years (SD = 2.12, range: 8-15) with a mean ADHD-RS of 15.9 (SD = 6.86, range 5-27). The go/no-go task was used to assess response inhibition, while functional near-infrared spectroscopy (fNIRS) was used to measure cerebral hemodynamics. Oxygenated hemoglobin (Oxy-Hb) values from fNIRS data were analyzed for each subject, focusing on past and current measurements. Baseline was set at 10 s pre-task, with interval means from 4 to 24 s analyzed. One-sample t-tests were used to evaluate brain activity magnitude. RESULTS: The results of the study demonstrate that the children who had discontinued the medication exhibited activation in specific brain regions including the frontopolar cortex and the right ventrolateral prefrontal cortex. Activation (t = 2.363, p = 0.034, Cohen's d = 0.632) was found especially in the right dorsolateral prefrontal cortex during the performance of the go/no-go task. These activated areas were consistent with those observed in a previous study comparing brain activity during a go/no-go task between children with ADHD and healthy children. CONCLUSION: The present study showed differences in cerebral hemodynamics before and after discontinuation of MPH in ADHD children whose ADHD symptoms did not recur after MPH was discontinued. In the near future, further investigations that include control groups will be conducted to demonstrate the effects of MPH prior to discontinuation based on the changes in cerebral blood flow in the right prefrontal cortex, which is involved in behavioral inhibition, as observed in this study. This and future research will facilitate the development of criteria for discontinuing treatment.

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  • Neural mechanisms of the relationship between aerobic fitness and working memory in older adults: An fNIRS study Reviewed

    Kazuki Hyodo, Ippeita Dan, Takashi Jindo, Kiyomitsu Niioka, Sho Naganawa, Ayako Mukoyama, Hideaki Soya, Takashi Arao

    Imaging Neuroscience   2   1 - 19   2024.5

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    Abstract

    A growing number of studies have revealed that higher aerobic fitness is associated with better working memory (WM) performance in older adults. However, the underlying functional neural mechanisms of this association remain under debate. It has been reported that aging increases recruitment of the prefrontal cortex (PFC) during cognitive tasks, and that this is associated with task performance in a compensatory manner. Therefore, this study aimed to clarify the prefrontal activation pattern that is associated with the relationship between aerobic fitness and WM performance in older adults, focusing on age-related extended prefrontal recruitment. Forty-seven older adults (65–74 years, 29 females) and 49 younger adults (18–24 years, 23 female) performed verbal and spatial n-back tasks, which included 0-, 1-, and 2-back conditions. Reaction time (RT) and accuracy (ACC) were assessed as indices of task performance. Prefrontal activation during the experimental tasks was monitored using functional near-infrared spectroscopy (fNIRS) and analyzed using an adaptive GLM method. We compared task performance and prefrontal activation between age groups to find age-related prefrontal activation patterns. Only older adults underwent a graded exercise test (GXT) to determine their ventilation thresholds (VT) as a measure of aerobic fitness, and, subsequently, the relationships among aerobic fitness, n-back task performance, and prefrontal activation in older adults were examined using correlation analysis and mediation analysis controlling for possible covariates. A comparison of task performance between groups revealed that older adults had slower RT and lower ACC than did younger adults, especially in the higher WM load 2-back condition. Group comparisons of prefrontal activation showed that older adults exhibited additional or greater activation than younger adults mainly in the ventrolateral PFC (VLPFC) and front polar area (FPA) in both the verbal and spatial 2-back conditions. Correlation analysis showed a relationship between higher VT, shorter RT for the verbal 2-back condition, and greater prefrontal activation of the bilateral FPA and right VLPFC during verbal 2-back conditions in older adults. In addition, mediation analyses indicated the possibility of a mediation effect of the prefrontal activation on the relationship between VT and RT for the verbal 2-back condition. These results suggest that older adults with higher aerobic fitness levels recruited more extended PFC regions, possibly for compensatory activation, to enhance their performance of the verbal n-back task. This study sheds light on the neural mechanisms underpinning the relationship between aerobic fitness and cognitive function in older adults.

    DOI： 10.1162/imag_a_00167

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  • Right prefrontal activation associated with deviations from expected lipstick texture assessed with functional near-infrared spectroscopy Reviewed

    Kazue Hirabayashi, Keith Kawabata Duncan, Keiko Tagai, Yasushi Kyutoku, Ippeita Dan

    Frontiers in Neuroergonomics   5   2024

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    DOI： 10.3389/fnrgo.2024.1331083

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  • Cerebral response to emotional working memory based on vocal cues: an fNIRS study Reviewed

    Saori Ohshima, Michihiko Koeda, Wakana Kawai, Hikaru Saito, Kiyomitsu Niioka, Koki Okuno, Sho Naganawa, Tomoko Hama, Yasushi Kyutoku, Ippeita Dan

    Frontiers in Human Neuroscience   17   2023.12

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    Introduction

    Humans mainly utilize visual and auditory information as a cue to infer others’ emotions. Previous neuroimaging studies have shown the neural basis of memory processing based on facial expression, but few studies have examined it based on vocal cues. Thus, we aimed to investigate brain regions associated with emotional judgment based on vocal cues using an N-back task paradigm.

    Methods

    Thirty participants performed N-back tasks requiring them to judge emotion or gender from voices that contained both emotion and gender information. During these tasks, cerebral hemodynamic response was measured using functional near-infrared spectroscopy (fNIRS).

    Results

    The results revealed that during the Emotion 2-back task there was significant activation in the frontal area, including the right precentral and inferior frontal gyri, possibly reflecting the function of an attentional network with auditory top-down processing. In addition, there was significant activation in the ventrolateral prefrontal cortex, which is known to be a major part of the working memory center.

    Discussion

    These results suggest that, compared to judging the gender of voice stimuli, when judging emotional information, attention is directed more deeply and demands for higher-order cognition, including working memory, are greater. We have revealed for the first time the specific neural basis for emotional judgments based on vocal cues compared to that for gender judgments based on vocal cues.

    DOI： 10.3389/fnhum.2023.1160392

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  • Exploring Japanese Consumers’ Motivators Related to Eating Soy Meat Reviewed

    Shoi TAKI, Narumi SAITO, Toru HANDA, Yuko MINAMI, Ippeita DAN, Yasushi KYUTOKU

    International Journal of Affective Engineering   2023

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    DOI： 10.5057/ijae.tjske-d-22-00075

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  • Impressions Evoked by Photographic Presentations of Hot-Spring Hotels in Prospective Japanese Tourists Reviewed

    Yasushi KYUTOKU, Alan YEN, Ippeita DAN

    International Journal of Affective Engineering   2023

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    DOI： 10.5057/ijae.tjske-d-22-00020

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  • Assessing functional impulsivity using functional near-infrared spectroscopy Reviewed

    Kenta Nakazawa, Kazue Hirabayashi, Wakana Kawai, Yasushi Kyutoku, Keith Kawabata Duncan, Ippeita Dan

    Frontiers in Neuroergonomics   4   2023

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    DOI： 10.3389/fnrgo.2023.1207484

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  • Optical imaging and spectroscopy for the study of the human brain: status report. Reviewed International journal

    Hasan Ayaz, Wesley B Baker, Giles Blaney, David A Boas, Heather Bortfeld, Kenneth Brady, Joshua Brake, Sabrina Brigadoi, Erin M Buckley, Stefan A Carp, Robert J Cooper, Kyle R Cowdrick, Joseph P Culver, Ippeita Dan, Hamid Dehghani, Anna Devor, Turgut Durduran, Adam T Eggebrecht, Lauren L Emberson, Qianqian Fang, Sergio Fantini, Maria Angela Franceschini, Jonas B Fischer, Judit Gervain, Joy Hirsch, Keum-Shik Hong, Roarke Horstmeyer, Jana M Kainerstorfer, Tiffany S Ko, Daniel J Licht, Adam Liebert, Robert Luke, Jennifer M Lynch, Jaume Mesquida, Rickson C Mesquita, Noman Naseer, Sergio L Novi, Felipe Orihuela-Espina, Thomas D O'Sullivan, Darcy S Peterka, Antonio Pifferi, Luca Pollonini, Angelo Sassaroli, João Ricardo Sato, Felix Scholkmann, Lorenzo Spinelli, Vivek J Srinivasan, Keith St Lawrence, Ilias Tachtsidis, Yunjie Tong, Alessandro Torricelli, Tara Urner, Heidrun Wabnitz, Martin Wolf, Ursula Wolf, Shiqi Xu, Changhuei Yang, Arjun G Yodh, Meryem A Yücel, Wenjun Zhou

    Neurophotonics   9 ( Suppl 2 )   S24001   2022.8

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    This report is the second part of a comprehensive two-part series aimed at reviewing an extensive and diverse toolkit of novel methods to explore brain health and function. While the first report focused on neurophotonic tools mostly applicable to animal studies, here, we highlight optical spectroscopy and imaging methods relevant to noninvasive human brain studies. We outline current state-of-the-art technologies and software advances, explore the most recent impact of these technologies on neuroscience and clinical applications, identify the areas where innovation is needed, and provide an outlook for the future directions.

    DOI： 10.1117/1.NPh.9.S2.S24001

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  • A deep convolutional neural network for estimating hemodynamic response function with reduction of motion artifacts in fNIRS. Reviewed International journal

    MinWoo Kim, Seonjin Lee, Ippeita Dan, Sungho Tak

    Journal of neural engineering   19 ( 1 )   2022.2

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    Objective. Functional near-infrared spectroscopy (fNIRS) is a neuroimaging technique for monitoring hemoglobin concentration changes in a non-invasive manner. However, subject movements are often significant sources of artifacts. While several methods have been developed for suppressing this confounding noise, the conventional techniques have limitations on optimal selections of model parameters across participants or brain regions. To address this shortcoming, we aim to propose a method based on a deep convolutional neural network (CNN).Approach. The U-net is employed as a CNN architecture. Specifically, large-scale training and testing data are generated by combining variants of hemodynamic response function (HRF) with experimental measurements of motion noises. The neural network is then trained to reconstruct hemodynamic response coupled to neuronal activity with a reduction of motion artifacts.Main results. Using extensive analysis, we show that the proposed method estimates the task-related HRF more accurately than the existing methods of wavelet decomposition and autoregressive models. Specifically, the mean squared error and variance of HRF estimates, based on the CNN, are the smallest among all methods considered in this study. These results are more prominent when the semi-simulated data contain variants of shapes and amplitudes of HRF.Significance. The proposed CNN method allows for accurately estimating amplitude and shape of HRF with significant reduction of motion artifacts. This method may have a great potential for monitoring HRF changes in real-life settings that involve excessive motion artifacts.

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  • Therapeutic Garden With Contemplative Features Induces Desirable Changes in Mood and Brain Activity in Depressed Adults. Reviewed International journal

    Agnieszka Olszewska-Guizzo, Anna Fogel, Nicolas Escoffier, Angelia Sia, Kenta Nakazawa, Akihiro Kumagai, Ippeita Dan, Roger Ho

    Frontiers in psychiatry   13   757056 - 757056   2022

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    The therapeutic values of contact with nature have been increasingly recognized. A growing body of evidence suggests that a unique subcategory of "contemplative landscapes" is particularly therapeutic. Previous studies predominantly focused on observational designs in non-clinical populations. It is not known if these effects can be extrapolated to populations suffering from depression, and experimental designs need to be utilized to establish causality. We examined the effects of in-situ passive exposure to three urban spaces on brain activity, namely a Therapeutic Garden with high Contemplative Landscape scores (TG), Residential Green (RG) and Busy Downtown (BD), and self-reported momentary mood in adults aged 21-74 (n = 92), including 24 clinically depressed and 68 healthy participants. Portable, multimodal electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS) systems were used to record brain activity, and a Profile of Mood States (POMS) questionnaire was used to record mood before and after exposure. We tested the interactions between the site, time and group for the mood, and between site and group for the neuroelectric oscillations and brain hemodynamics. Self-reported pre- post-mood was significant only at the TG (p = 0.032) in both groups. The lowest Total Mood Disturbance (TMD) was reported at TG and the highest in BD (p = 0.026). Results from fNIRS indicated marginally significant lower oxy-Hb in the frontal region at TG as compared to BD (p = 0.054) across both groups. The marginally significant effect of site and group was also observed (p = 0.062), with the Clinical group showing much lower oxy-Hb at TG than Healthy. The opposite pattern was observed at BD. EEG results showed differences between Healthy and Clinical groups in the Frontal Alpha Asymmetry (FAA) pattern across the sites (p = 0.04), with more frontal alpha right in the Clinical sample and more left lateralization in the Healthy sample at TG. Temporal Beta Asymmetry (TBA) analyses suggested that patients displayed lower bottom-up attention than Healthy participants across all sites (p = 0.039). The results suggest that both healthy and depressed adults benefitted from exposure to TG, with possibly different pathways of mood improvement. Visiting therapeutic nature with contemplative features may provide valuable support for the treatment of depression in clinical populations and a self-care intervention in non-clinical populations.

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  • A Willingness-to-Pay Associated Right Prefrontal Activation During a Single, Real Use of Lipsticks as Assessed Using Functional Near-Infrared Spectroscopy Reviewed

    Kazue Hirabayashi, Tatsuya Tokuda, Tomomi Nishinuma, Keith Kawabata Duncan, Keiko Tagai, Ippeita Dan

    Frontiers in Neuroergonomics   2021.11

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    <jats:p>Understanding consumer preferences and behavior is a major goal of consumer-oriented companies. The application of neuroscience to this goal is a promising avenue for companies. Previously, we observed a positive correlation during actual cosmetic use between the right dorsolateral prefrontal cortex (dlPFC) activity, measured by functional near-infrared spectroscopy (fNIRS), and the associated willingness-to-pay (WTP) values. However, we were unable to find any consistent group differences in the right dlPFC between different powdery foundations. Thus, the main objective of this study was to replicate the previous study and in addition, we aimed to refine the method of the previous study to increase the chance that a difference in valuation between different products can be detected. Twenty-five frequent lipstick using females were asked to apply six different lipsticks to their lips and to record how much they were willing to pay. To maximize the variation of the subjective experience of the products and the associated brain activity, the most preferred color lipstick and a less preferred color lipstick were chosen for each participant, and each color of lipstick had three different textures (<jats:italic>Lo, Mid</jats:italic>, and <jats:italic>Hi</jats:italic>). The time series was analyzed with the general linear model (GLM) and the correlation between the right dlPFC beta scores for the lipsticks and their respective WTP values conducted for each participant. This revealed a significant positive correlation and replicated our previous study. Surprisingly, the lipstick color and the texture manipulations did not result in any consistent differences in WTP and similarly no consistent group differences in brain activations. This study replicates our previous study extending it to a different type of cosmetic. The right dlPFC activity during the use of cosmetics may be a potential brain-based personalization or product selection process biomarker.</jats:p>

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  • Visualizing Neuropharmacological Effects of Guanfacine Extended Release in Attention Deficit Hyperactivity Disorder Using Functional Near-Infrared Spectroscopy Reviewed

    Takahiro Ikeda, Akari Inoue, Daisuke Tanaka, Tamao Hashimoto, Stephanie Sutoko, Tatsuya Tokuda, Yasushi Kyutoku, Atsushi Maki, Takanori Yamagata, Ippeita Dan, Yukifumi Monden

    Frontiers in Neuroergonomics   2   2021.7

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    <bold>Objective:</bold> In the current study, we explored the neural substrate for acute effects of guanfacine extended release (GXR) on inhibitory control in school-aged children with attention deficit hyperactivity disorder (ADHD), using functional near-infrared spectroscopy (fNIRS).

    <bold>Methods:</bold> Following a GXR washout period, 12 AD HD children (6–10 years old) performed a go/no-go task before and 3 h after GXR or placebo administration, in a randomized, double-blind, placebo-controlled, crossover design study. In the primary analysis, fNIRS was used to monitor the right prefrontal cortical hemodynamics of the participants, where our former studies showed consistent dysfunction and osmotic release oral system-methylphenidate (OROS-MPH) and atomoxetine hydrochloride (ATX) elicited recovery. We examined the inter-medication contrast, comparing the effect of GXR against the placebo. In the exploratory analysis, we explored neural responses in regions other than the right prefrontal cortex (PFC).

    <bold>Results:</bold> In the primary analysis, we observed no significant main effects or interactions of medication type and age in month (two-way mixed ANCOVA, <italic>Fs</italic> &amp;lt; 0.20, all <italic>ps</italic> &amp;gt; .05). However, in the <italic>post-hoc</italic> analysis, we observed significant change in the oxy-Hb signal in the right angular gyrus (AG) for inter-medication (one sample <italic>t</italic>-test, <italic>p</italic> &amp;lt; 0.05, uncorrected, Cohen's <italic>d</italic> = 0.71).

    <bold>Conclusions:</bold> These results are different from the neuropharmacological effects of OROS-MPH and ATX, which, in an upregulated manner, reduced right PFC function in ADHD children during inhibitory tasks. This analysis, while limited by its secondary nature, suggested that the improved cognitive performance was associated with activation in the right AG, which might serve as a biological marker to monitor the effect of GXR in the ADHD children.

    DOI： 10.3389/fnrgo.2021.657657

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  • Hemodynamic Response to Three Types of Urban Spaces before and after Lockdown during the COVID-19 Pandemic. Reviewed International journal

    Agnieszka Olszewska-Guizzo, Ayako Mukoyama, Sho Naganawa, Ippeita Dan, Syeda Fabeha Husain, Cyrus S Ho, Roger Ho

    International journal of environmental research and public health   18 ( 11 )   2021.6

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    (1) Background: Prolonged lockdowns with stay-at-home orders have been introduced in many countries since the outbreak of the COVID-19 pandemic. They have caused a drastic change in the everyday lives of people living in urbanized areas, and are considered to contribute to a modified perception of the public space. As research related to the impact of COVID-19 restrictions on mental health and well-being emerges, the associated longitudinal changes of brain hemodynamics in healthy adults remain largely unknown. (2) Methods: this study examined the hemodynamic activation patterns of the prefrontal and occipital cortices of 12 participants (5 male, Mage = 47.80, SDage = 17.79, range 25 to 74, and 7 female, Mage = 39.00, SDage = 18.18, range 21 to 65) passively viewing videos from three urban sites in Singapore (Urban Park, Neighborhood Landscape and City Center) at two different time points-T1, before the COVID-19 pandemic and T2, soon after the lockdown was over. (3) Results: We observed a significant and marginally significant decrease in average oxyhemoglobin (Oxy-Hb) over time for each of the visual conditions. For both green spaces (Urban Park and Neighborhood Landscape), the decrease was in the visual cortex, while for the City Center with no green elements, the marginal decrease was observed in the visual cortex and the frontal eye fields. (4) Conclusions: The results suggest that the COVID-19-related lockdown experienced by urban inhabitants may have contributed to decreased brain hemodynamics, which are further related to a heightened risk of mental health disorders, such as depression or a decline in cognitive functions. Moreover, the busy City Center scenes induced a hemodynamic pattern associated with stress and anxiety, while urban green spaces did not cause such an effect. Urban green scenes can be an important factor to offset the negative neuropsychological impact of busy urban environments post-pandemic.

    DOI： 10.3390/ijerph18116118

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  • Native non-prototypicality in vowel perception induces prominent neuromagnetic mismatch intensities in non-native speakers: a pilot study. Reviewed International journal

    Mikio Kubota, Junko Matsuzaki, Ippeita Dan, Haruka Dan, George Zouridakis

    Experimental brain research   239 ( 3 )   937 - 953   2021.3

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    Neural mismatch response resulting from the difference between prediction and observation is related to change detection and discrimination. Robust neuromagnetic brain activity of auditory mismatch-related perception occurs in response to non-prototypical vowels in across-category contrasts for first-language speakers. However, whether this non-prototypicality effect applies to within-category vowel perception remains to be elucidated. Here, healthy Japanese adults (n = 7) were subjected to magnetoencephalography (MEG) while watching a silent movie, and passively listened to synthesized English vowels /i/. We observed the source-level mismatch effect to the mid-high near-front vowel deviant [ɪ] with the most non-prototypical, unspecified feature in the participants' native language system. The mismatch effect recruited the left posterior superior temporal sulcus with a peak latency of 225 ms post-stimulus onset. We further studied whether a longer F1 distance between vowel pairs would increase mismatch-activated intensities, however, we did not observe neuromagnetic changes when the prototypical anchor standard [i] was compared with three non-prototypical deviants differing in first resonance frequency (F1) values. Our results indicate that an F1 increase in within-category upper front vowel perception is a strong activator of mismatch responses measured by source-level activated intensities for non-native listeners.

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  • Errata: Best practices for fNIRS publications. Reviewed International journal

    Meryem A Yücel, Alexander V Lühmann, Felix Scholkmann, Judit Gervain, Ippeita Dan, Hasan Ayaz, David Boas, Robert J Cooper, Joseph Culver, Clare E Elwell, Adam Eggebrecht, Maria A Franceschini, Christophe Grova, Fumitaka Homae, Frédéric Lesage, Hellmuth Obrig, Ilias Tachtsidis, Sungho Tak, Yunjie Tong, Alessandro Torricelli, Heidrun Wabnitz, Martin Wolf

    Neurophotonics   8 ( 1 )   019802 - 019802   2021.1

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    [This corrects the article DOI: 10.1117/1.NPh.8.1.012101.].

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  • Trajectories of Posttraumatic Growth and Their Associations With Quality of Life After the 2011 Tohoku Earthquake and Tsunami Reviewed International journal

    Yasushi Kyutoku, Ippeita Dan, Mitsuru Yamashina, Ren Komiyama, Angela J. Liegey-Dougall

    JOURNAL OF TRAUMATIC STRESS   2020.11

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    DOI： 10.1002/jts.22628

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  • Head errors of syntactic dependency increase neuromagnetic mismatch intensities Reviewed International journal

    Mikio Kubota, Junko Matsuzaki, Ippeita Dan, Haruka Dan, George Zouridakis

    EXPERIMENTAL BRAIN RESEARCH   238 ( 10 )   2137 - 2160   2020.10

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    DOI： 10.1007/s00221-020-05872-1

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  • Using a Data-Driven Approach to Estimate Second-Language Proficiency From Brain Activation: A Functional Near-Infrared Spectroscopy Study Reviewed International journal

    Miaomei Lei, Toshinori Miyoshi, Ippeita Dan, Hiroki Sato

    FRONTIERS IN NEUROSCIENCE   14   694 - 694   2020.7

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    DOI： 10.3389/fnins.2020.00694

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  • Acute administration of methylphenidate differentially affects cortical processing of emotional facial expressions in attention-deficit hyperactivity disorder children as studied by functional near-infrared spectroscopy. Reviewed International journal

    Megumi Kobayashi, Takahiro Ikeda, Tatsuya Tokuda, Yukifumi Monden, Masako Nagashima, Sakae G Mizushima, Takeshi Inoue, Keiichi Shimamura, Yuta Ujiie, Akari Arakawa, Chie Kuroiwa, Mayuko Ishijima, Yuki Kishimoto, So Kanazawa, Takanori Yamagata, Masami K Yamaguchi, Ryoichi Sakuta, Ippeita Dan

    Neurophotonics   7 ( 2 )   025003 - 025003   2020.4

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    Significance: It has been reported that children with attention-deficit hyperactivity disorder (ADHD) have impairment in the recognition of angry but not of happy facial expressions, and they show atypical cortical activation patterns in response to facial expressions. However, little is known about neural mechanisms underlying the impaired recognition of facial expressions in school-aged children with ADHD and the effects of acute medication on their processing of facial expressions. Aim: We aimed to investigate the possibility that acute administration of methylphenidate (MPH) affects processing of facial expressions in ADHD children. Approach: We measured the hemodynamic changes in the bilateral temporo-occipital areas of ADHD children observing the happy and angry facial expressions before and 1.5 h after MPH or placebo administration in a randomized, double-blind, placebo-controlled, crossover design study. Results: We found that, regardless of medication, happy expressions induced increased oxyhemoglobin (oxy-Hb) responses in the right inferior occipital region but not in the superior temporal region. For angry expressions, oxy-Hb responses increased after MPH administration, but not after placebo administration, in the left inferior occipital area, whereas there was no significant activation before MPH administration. Conclusions: Our results suggest that (1) ADHD children consistently recruit the right inferior occipital regions to process happy expressions and (2) MPH administration to ADHD children enhances cortical activation in the left inferior occipital regions when they process angry expressions.

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  • Atypical Dynamic-Connectivity Recruitment in Attention-Deficit/Hyperactivity Disorder Children: An Insight Into Task-Based Dynamic Connectivity Through an fNIRS Study Reviewed International journal

    Stephanie Sutoko, Yukifumi Monden, Tatsuya Tokuda, Takahiro Ikeda, Masako Nagashima, Tsukasa Funane, Hirokazu Atsumori, Masashi Kiguchi, Atsushi Maki, Takanori Yamagata, Ippeita Dan

    FRONTIERS IN HUMAN NEUROSCIENCE   14   3 - 3   2020.1

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  • Maternal speech shapes the cerebral frontotemporal network in neonates: A hemodynamic functional connectivity study Reviewed International journal

    Mariko Uchida-Ota, Takeshi Arimitsu, Daisuke Tsuzuki, Ippeita Dan, Kazushige Ikeda, Takao Takahashi, Yasuyo Minagawa

    DEVELOPMENTAL COGNITIVE NEUROSCIENCE   39   100701 - 100701   2019.10

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    DOI： 10.1016/j.dcn.2019.100701

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  • Exploring attentive task-based connectivity for screening attention deficit/hyperactivity disorder children: a functional near-infrared spectroscopy study Reviewed International journal

    Stephanie Sutoko, Yukifumi Monden, Tatsuya Tokuda, Takahiro Ikeda, Masako Nagashima, Tsukasa Funane, Hiroki Sato, Masashi Kiguchi, Atsushi Maki, Takanori Yamagata, Ippeita Dan

    NEUROPHOTONICS   6 ( 4 )   045013 - 045013   2019.10

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    DOI： 10.1117/1.NPh.6.4.045013

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  • Biases in paired preference tests: Cross-cultural comparison of Japanese and American consumers Reviewed

    Yuka Hasegawa, Rie Ishii, Yasushi Kyutoku, Ippeita Dan, Benoit Rousseau

    JOURNAL OF SENSORY STUDIES   34 ( 3 )   2019.6

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    DOI： 10.1111/joss.12498

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  • Distinct Methylphenidate-Evoked Response Measured Using Functional Near-Infrared Spectroscopy During Go/No-Go Task as a Supporting Differential Diagnostic Tool Between Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder Comorbid Children Reviewed International journal

    Stephanie Sutoko, Yukifumi Monden, Tatsuya Tokuda, Takahiro Ikeda, Masako Nagashima, Masashi Kiguchi, Atsushi Maki, Takanori Yamagata, Ippeita Dan

    FRONTIERS IN HUMAN NEUROSCIENCE   13   7 - 7   2019.2

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  • Adaptive algorithm utilizing acceptance rate for eliminating noisy epochs in block-design functional near-infrared spectroscopy data: application to study in attention deficit/hyperactivity disorder children Reviewed International journal

    Stephanie Sutoko, Yukifumi Monden, Tsukasa Funane, Tatsuya Tokuda, Takusige Katura, Hiroki Sato, Masako Nagashima, Masashi Kiguchi, Atsushi Maki, Takanori Yamagata, Ippeita Dan

    NEUROPHOTONICS   5 ( 4 )   045001 - 045001   2018.10

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    DOI： 10.1117/1.NPh.5.4.045001

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  • Comprehension-Dependent Cortical Activation During Speech Comprehension Tasks with Multiple Languages: Functional Near-Infrared Spectroscopy Study Reviewed

    Miaomei Lei, Toshinori Miyoshi, Yoshiki Niwa, Ippeita Dan, Hiroki Sato

    JAPANESE PSYCHOLOGICAL RESEARCH   60 ( 4 )   300 - 310   2018.10

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    DOI： 10.1111/jpr.12218

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  • Mental representation of domestic cooking operations among Japanese consumers Reviewed

    Yuko Minami, Yasushi Kyutoku, Masako Okamoto, Yuko Kusakabe, Takeshi Koizumi, Ippeita Dan

    INTERNATIONAL JOURNAL OF GASTRONOMY AND FOOD SCIENCE   13   38 - 46   2018.10

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    DOI： 10.1016/j.ijgfs.2018.05.005

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  • Hypoactivation of the Right Prefrontal Cortex Underlying Motor-Related Inhibitory Deficits in Children with Autism Spectrum Disorder: A Functional Near-Infrared Spectroscopy Study Reviewed

    Takahiro Ikeda, Tatsuya Tokuda, Yukifumi Monden, Masahiro Hirai, Sakae G. Mizushima, Masako Nagashima, Yasushi Kyutoku, Takamichi Taniguchi, Hideo Shimoizumi, Ippeita Dan, Takanori Yamagata

    JAPANESE PSYCHOLOGICAL RESEARCH   60 ( 4 )   251 - 264   2018.10

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    DOI： 10.1111/jpr.12204

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  • Cerebral Hemodynamic Response During Concealment of Information About a Mock Crime: Application of a General Linear Model With an Adaptive Hemodynamic Response Function Reviewed

    Kiyomitsu Niioka, Minako Uga, Taihei Nagata, Tatsuya Tokuda, Ippeita Dan, Keita Ochi

    JAPANESE PSYCHOLOGICAL RESEARCH   60 ( 4 )   311 - 326   2018.10

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    DOI： 10.1111/jpr.12194

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  • Atypical neural modulation in the right prefrontal cortex during an inhibitory task with eye gaze in autism spectrum disorder as revealed by functional near-infrared spectroscopy Reviewed International journal

    Takahiro Ikeda, Masahiro Hirai, Takeshi Sakurada, Yukifumi Monden, Tatsuya Tokuda, Masako Nagashima, Hideo Shimoizumi, Ippeita Dan, Takanori Yamagata

    NEUROPHOTONICS   5 ( 3 )   035008 - 035008   2018.7

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    DOI： 10.1117/1.NPh.5.3.035008

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  • Classification of strawberry fruit shape by machine learning

    T. Ishikawa, A. Hayashi, S. Nagamatsu, Y. Kyutoku, I. Dan, T. Wada, K. Oku, Y. Saeki, T. Uto, T. Tanabata, S. Isobe, N. Kochi

    International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences - ISPRS Archives   42 ( 2 )   463 - 470   2018.5

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    DOI： 10.5194/isprs-archives-XLII-2-463-2018

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  • Neural basis for reduced executive performance with hypoxic exercise Reviewed International journal

    Genta Ochi, Yuhki Yamada, Kazuki Hyodo, Kazuya Suwabe, Takemune Fukuie, Kyeongho Byun, Ippeita Dan, Hideaki Soya

    NEUROIMAGE   171   75 - 83   2018.5

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    DOI： 10.1016/j.neuroimage.2017.12.091

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  • Methylphenidate-Elicited Distinct Neuropharmacological Activation Patterns Between Medication-Naive Attention Deficit Hyperactivity Disorder Children With and Without Comorbid Autism Spectrum Disorder: A Functional NearInfrared Spectroscopy Study Reviewed

    Tokuda, T, Ikeda, T, Monden, Y, Mizushima, S. G, Inoue, T, Nagashima, M, Shimamura, K, Arakawa, A, Kobayashi, M, Kuroiwa, C, Ujiie, Y, Dan, H, Kyutoku, Y, Taniguchi, T, Shimoizumi, H, Yamagata, T, Yamaguchi, M. K, Kanazawa, S, Sakuta, R, Dan, I

    Neuropsychiatry   8 ( 2 )   739 - 744   2018.4

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    DOI： 10.4172/neuropsychiatry.1000418

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  • A transferable high-intensity intermittent exercise improves executive performance in association with dorsolateral prefrontal activation in young adults Reviewed International journal

    Sylwester Kujach, Kyeongho Byun, Kazuki Hyodo, Kazuya Suwabe, Takemune Fukuie, Radoslaw Laskowski, Ippeita Dan, Hideaki Soya

    NEUROIMAGE   169   117 - 125   2018.4

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    DOI： 10.1016/j.neuroimage.2017.12.003

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  • Explicit Performance in Girls and Implicit Processing in Boys: A Simultaneous fNIRS-ERP Study on Second Language Syntactic Learning in Young Adolescents Reviewed International journal

    Lisa Sugiura, Masahiro Hata, Hiroko Matsuba-Kurita, Minako Uga, Daisuke Tsuzuki, Ippeita Dan, Hiroko Hagiwara, Fumitaka Homae

    FRONTIERS IN HUMAN NEUROSCIENCE   12   62 - 62   2018.3

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    DOI： 10.3389/fnhum.2018.00062

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  • Exploring Tourists' Perceptions of Traditional and Contemporary Hot Springs Hotels in Japan Reviewed

    Chih-Lun (Alan) Yen, Yasushi Kyutoku, Ippeita Dan

    INTERNATIONAL JOURNAL OF HOSPITALITY AND TOURISM ADMINISTRATION   19 ( 3 )   336 - 360   2018

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    DOI： 10.1080/15256480.2017.1324341

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  • Categorical Nature of Consumer Price Estimations of Postharvest Bruised Apples Reviewed

    Yasushi Kyutoku, Naoko Hasegawa, Ippeita Dan, Hiroaki Kitazawa

    JOURNAL OF FOOD QUALITY   2018

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    DOI： 10.1155/2018/3572397

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  • Macroanatomical Landmarks Featuring Junctions of Major Sulci and Fissures and Scalp Landmarks Based on the International 10-10 System for Analyzing Lateral Cortical Development of Infants Reviewed International journal

    Daisuke Tsuzuki, Fumitaka Homae, Gentaro Taga, Hama Watanabe, Mie Matsui, Ippeita Dan

    FRONTIERS IN NEUROSCIENCE   11   394 - 394   2017.7

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    DOI： 10.3389/fnins.2017.00394

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  • Detection of resting state functional connectivity using partial correlation analysis: A study using multi-distance and whole-head probe near-infrared spectroscopy Reviewed International journal

    Eisuke Sakakibara, Fumitaka Homae, Shingo Kawasaki, Yukika Nishimura, Ryu Takizawa, Shinsuke Koike, Akihide Kinoshita, Hanako Sakurada, Mika Yamagishi, Fumichika Nishimura, Akane Yoshikawa, Aya Inai, Masaki Nishioka, Yosuke Eriguchi, Jun Matsuoka, Yoshihiro Satomura, Naohiro Okada, Chihiro Kakiuchi, Tsuyoshi Araki, Chiemi Kan, Maki Umeda, Akihito Shimazu, Minako Uga, Ippeita Dan, Hideki Hashimoto, Norito Kawakami, Kiyoto Kasai

    NEUROIMAGE   142   590 - 601   2016.11

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    DOI： 10.1016/j.neuroimage.2016.08.011

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  • MinR 10/20 system: Quantitative and reproducible cranial landmark setting method for MRI based on minimum initial reference points Reviewed International journal

    Daisuke Tsuzuki, Hama Watanabe, Ippeita Dan, Gentaro Taga

    JOURNAL OF NEUROSCIENCE METHODS   264   86 - 93   2016.5

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    DOI： 10.1016/j.jneumeth.2016.02.024

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  • The association between aerobic fitness and cognitive function in older men mediated by frontal lateralization Reviewed International journal

    Kazuki Hyodo, Ippeita Dan, Yasushi Kyutoku, Kazuya Suwabe, Kyeongho Byun, Genta Ochi, Morimasa Kato, Hideaki Soya

    NEUROIMAGE   125   291 - 300   2016.1

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    DOI： 10.1016/j.neuroimage.2015.09.062

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  • Rice deprivation affects rice cravings in Japanese people Reviewed

    Sakura Komatsu, Yasushi Kyutoku, Ippeita Dan, Kenjiro Aoyama

    FOOD QUALITY AND PREFERENCE   46   9 - 16   2015.12

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    DOI： 10.1016/j.foodqual.2015.06.007

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  • Effects of Sex and Proficiency in Second Language Processing as Revealed by a Large-Scale fNIRS Study of School-Aged Children Reviewed International journal

    Lisa Sugiura, Shiro Ojima, Hiroko Matsuba-Kurita, Ippeita Dan, Daisuke Tsuzuki, Takusige Katura, Hiroko Hagiwara

    HUMAN BRAIN MAPPING   36 ( 10 )   3890 - 3911   2015.10

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    DOI： 10.1002/hbm.22885

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  • Determination of epileptic focus side in mesial temporal lobe epilepsy using long-term noninvasive fNIRS/EEG monitoring for presurgical evaluation Reviewed International journal

    Edmi Edison Rizki, Minako Uga, Ippeita Dan, Haruka Dan, Daisuke Tsuzuki, Hidenori Yokota, Keiji Oguro, Eiju Watanabe

    NEUROPHOTONICS   2 ( 2 )   025003 - 025003   2015.4

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    DOI： 10.1117/1.NPh.2.2.025003

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  • Anatomical guidance for functional near-infrared spectroscopy: AtlasViewer tutorial Reviewed International journal

    Christopher M. Aasted, Meryem A. Yuecel, Robert J. Cooper, Jay Dubb, Daisuke Tsuzuki, Lino Becerra, Mike P. Petkov, David Borsook, Ippeita Dan, David A. Boas

    NEUROPHOTONICS   2 ( 2 )   020801 - 020801   2015.4

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    DOI： 10.1117/1.NPh.2.2.020801

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  • Exploring effective multiplicity in multichannel functional near-infrared spectroscopy using eigenvalues of correlation matrices Reviewed International journal

    Minako Uga, Ippeita Dan, Haruka Dan, Yasushi Kyutoku, Y-h Taguchi, Eiju Watanabe

    NEUROPHOTONICS   2 ( 1 )   015002 - 015002   2015.1

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    DOI： 10.1117/1.NPh.2.1.015002

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  • Positive effect of acute mild exercise on executive function via arousal-related prefrontal activations: An fNIRS study Reviewed International journal

    Kyeongho Byun, Kazuld Hyodo, Kazuya Suwabe, Genta Ochi, Yosuke Sakairi, Morimasa Kato, Ippeita Dan, Hideaki Soya

    NEUROIMAGE   98   336 - 345   2014.9

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    DOI： 10.1016/j.neuroimage.2014.04.067

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  • Direct cortical hemodynamic mapping of somatotopy of pig nostril sensation by functional near-infrared cortical imaging (fNCI) Reviewed International journal

    Minako Uga, Toshiyuki Saito, Toshifumi Sano, Hidenori Yokota, Keiji Oguro, Edmi Edison Rizki, Tsutomu Mizutani, Takusige Katura, Ippeita Dan, Eiju Watanabe

    NEUROIMAGE   91   138 - 145   2014.5

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    DOI： 10.1016/j.neuroimage.2013.12.062

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  • Referential framework for transcranial anatomical correspondence for fNIRS based on manually traced sulci and gyri of an infant brain Reviewed International journal

    Mie Matsui, Fumitaka Homae, Daisuke Tsuzuki, Hama Watanabe, Masatoshi Katagiri, Satoshi Uda, Mitsuhiro Nakashima, Ippeita Dan, Gentaro Taga

    NEUROSCIENCE RESEARCH   80   55 - 68   2014.3

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    DOI： 10.1016/j.neures.2014.01.003

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  • Analyzing comprehensive palatability of cheese products by multivariate regression to its subdomains. Reviewed International journal

    Kumiko Nakano, Yasushi Kyutoku, Minako Sawa, Shigenobu Matsumura, Ippeita Dan, Tohru Fushiki

    Food science & nutrition   1 ( 5 )   369 - 76   2013.9

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    The present study explored the possibility of generating a novel sensory evaluation instrument for describing comprehensive food palatability via its subdomains (rewarding, cultural, and informational) while keeping physiological factors constant. Seventy-five Japanese participants were asked to taste cheese samples and to respond to a questionnaire that was developed to dissect the distinct subdomains of palatability. The subsequent factor analyses revealed that three major factors may serve as distinct subdomains of palatability: rewarding, cultural, and informational, although the informational factor was not sufficiently robust. Multivariate regression analysis on cheese samples with exactly the same ingredients but sold in different packages led to different comprehensive palatability ratings due to the contribution of the cultural, but not the rewarding, factor. These results suggest that palatability is not merely determined by the physical and chemical properties that are intrinsic to a food product itself, but also depends on psychological properties that can arise through interaction between humans and the food product. The current study presents the first experimental demonstration that palatability could be dissociated to its subdomains.

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  • Language-specific cortical activation patterns for verbal fluency tasks in Japanese as assessed by multichannel functional near-infrared spectroscopy Reviewed International journal

    Haruka Dan, Ippeita Dan, Toshifumi Sano, Yasushi Kyutoku, Keiji Oguro, Hidenori Yokota, Daisuke Tsuzuki, Eiju Watanabe

    BRAIN AND LANGUAGE   126 ( 2 )   208 - 216   2013.8

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    DOI： 10.1016/j.bandl.2013.05.007

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  • Memory Color Effect Induced by Familiarity of Brand Logos Reviewed International journal

    Atsushi Kimura, Yuji Wada, Tomohiro Masuda, Sho-ichi Goto, Daisuke Tsuzuki, Haruo Hibino, Dongsheng Cai, Ippeita Dan

    PLOS ONE   8 ( 7 )   e68474   2013.7

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    DOI： 10.1371/journal.pone.0068474

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  • Effect of auditory input on activations in infant diverse cortical regions during audiovisual processing Reviewed International journal

    Hama Watanabe, Fumitaka Homae, Tamami Nakano, Daisuke Tsuzuki, Lkhamsuren Enkhtur, Kiyotaka Nemoto, Ippeita Dan, Gentaro Taga

    HUMAN BRAIN MAPPING   34 ( 3 )   543 - 565   2013.3

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    DOI： 10.1002/hbm.21453

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  • Extrinsic information influences taste and flavor perception: A review from psychological and neuroimaging perspectives Reviewed International journal

    Masako Okamoto, Ippeita Dan

    SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY   24 ( 3 )   247 - 255   2013.3

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    DOI： 10.1016/j.semcdb.2012.11.001

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  • Superiority of Experts Over Novices in Trueness and Precision of Concentration Estimation of Sodium Chloride Solutions Reviewed International journal

    Tomohiro Masuda, Yuji Wada, Masako Okamoto, Yasushi Kyutoku, Yui Yamaguchi, Atsushi Kimura, Tatsu Kobayakawa, Takayuki Kawai, Ippeita Dan, Fumiyo Hayakawa

    CHEMICAL SENSES   38 ( 3 )   251 - 258   2013.3

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    DOI： 10.1093/chemse/bjs137

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  • Evoked potential mapping of the rostral region by frameless navigation system in Mexican hairless pig Reviewed International journal

    Toshiyuki Saito, Minako Uga, Daisuke Tsuzuki, Hidenori Yokota, Keiji Oguro, Tsuyoshi Yamamoto, Ippeita Dan, Eiju Watanabe

    JOURNAL OF NEUROSCIENCE METHODS   212 ( 1 )   100 - 105   2013.1

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    DOI： 10.1016/j.jneumeth.2012.09.027

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  • Effect of anesthesia on trigeminal somatosensory evoked magnetic fields Reviewed

    Otsuka T, Dan H, Dan I, Sase M, Sano T, Tsuzuki D, Sasaguri K, Okada N, Kusama M, Jinbu Y, Watanabe E

    Journal of Dental Research   91 ( 12 )   196 - 220   2012.12

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  • Acute moderate exercise enhances compensatory brain activation in older adults Reviewed International journal

    Kazuki Hyodo, Ippeita Dan, Kazuya Suwabe, Yasushi Kyutoku, Yuhki Yamada, Mitsuya Akahori, Kyeongho Byun, Morimasa Kato, Hideaki Soya

    NEUROBIOLOGY OF AGING   33 ( 11 )   2621 - 2632   2012.11

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    DOI： 10.1016/j.neurobiolaging.2011.12.022

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  • Reaction time as an indicator of stimulus-response binding in affective judgment of visual stimuli Reviewed

    Atsushi Kimura, Ippeita Dan, Nobuyuki Watanabe, Hiroshi Yamada, Yuji Wada

    JAPANESE PSYCHOLOGICAL RESEARCH   54 ( 4 )   335 - 347   2012.11

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    DOI： 10.1111/j.1468-5884.2012.00511.x

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  • Effects of environmental context on temporal perception bias in apparent motion Reviewed

    Kimura A, Dan I

    Japanese Psychological Research   54 ( 4 )   335 - 347   2012.10

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  • Validating atlas-guided DOT: A comparison of diffuse optical tomography informed by atlas and subject-specific anatomies Reviewed International journal

    Robert J. Cooper, Matteo Caffini, Jay Dubb, Qianqian Fang, Anna Custo, Daisuke Tsuzuki, Bruce Fischl, William Wells, Ippeita Dan, David A. Boas

    NEUROIMAGE   62 ( 3 )   1999 - 2006   2012.9

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    DOI： 10.1016/j.neuroimage.2012.05.031

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  • Health numeracy in Japan: measures of basic numeracy account for framing bias in a highly numerate population Reviewed International journal

    Masako Okamoto, Yasushi Kyutoku, Manabu Sawada, Lester Clowney, Eiju Watanabe, Ippeita Dan, Keiko Kawamoto

    BMC MEDICAL INFORMATICS AND DECISION MAKING   12   104 - 104   2012.9

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    DOI： 10.1186/1472-6947-12-104

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  • Adaptive Hemodynamic Response Function to Optimize Differential Temporal Information of Hemoglobin Signals in Functional Near-Infrared Spectroscopy Reviewed

    Sano t, Tsuzuki D, Dan I, Dan H, Yokota H, Oguro K, Watanabe E

    proceeding of IEEE/ICME International Conference on Complex Medical Engineering,2012.CME 2012   788 - 92   2012.7

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  • Multichannel fNIRS assessment of overt and covert confrontation naming Reviewed International journal

    Ayano Moriai-Izawa, Haruka Dan, Ippeita Dan, Toshifumi Sano, Keiji Oguro, Hidenori Yokota, Daisuke Tsuzuki, Eiju Watanabe

    BRAIN AND LANGUAGE   121 ( 3 )   185 - 193   2012.6

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    DOI： 10.1016/j.bandl.2012.02.001

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  • Clinically-oriented monitoring of acute effects of methylphenidate on cerebral hemodynamics in ADHD children using fNIRS Reviewed International journal

    Yukifumi Monden, Haruka Dan, Masako Nagashima, Ippeita Dan, Yasushi Kyutoku, Masako Okamoto, Takanori Yamagata, Mariko Y. Momoi, Eiju Watanabe

    CLINICAL NEUROPHYSIOLOGY   123 ( 6 )   1147 - 1157   2012.6

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    DOI： 10.1016/j.clinph.2011.10.006

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  • Dish influences implicit gender-based food stereotypes among young Japanese adults Reviewed International journal

    Atsushi Kimura, Yuji Wada, Akio Asakawa, Tomohiro Masuda, Sho-ichi Goto, Ippeita Dan, Takashi Oka

    APPETITE   58 ( 3 )   940 - 945   2012.6

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    DOI： 10.1016/j.appet.2012.02.013

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  • Conceptualization of food choice motives and consumption among Japanese in light of meal, gender, and age effects Reviewed

    Yasushi Kyutoku, Yuko Minami, Takeshi Koizumi, Masako Okamoto, Yuko Kusakabe, Ippeita Dan

    FOOD QUALITY AND PREFERENCE   24 ( 1 )   213 - 217   2012.4

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    DOI： 10.1016/j.foodqual.2011.10.002

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  • Package images modulate flavors in memory: Incidental learning of fruit juice flavors Reviewed

    Nanami Mizutani, Ippeita Dan, Yasushi Kyutoku, Daisuke Tsuzuki, Lester Clowney, Yuko Kusakabe, Masako Okamoto, Toshimasa Yamanaka

    FOOD QUALITY AND PREFERENCE   24 ( 1 )   92 - 98   2012.4

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    DOI： 10.1016/j.foodqual.2011.09.007

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  • Stable and convenient spatial registration of stand-alone NIRS data through anchor-based probabilistic registration Reviewed International journal

    Daisuke Tsuzuki, Dong-sheng Cai, Haruka Dan, Yasushi Kyutoku, Akifumi Fujita, Eiju Watanabe, Ippeita Dan

    NEUROSCIENCE RESEARCH   72 ( 2 )   163 - 171   2012.2

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    DOI： 10.1016/j.neures.2011.10.008

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  • Sound to Language: Different Cortical Processing for First and Second Languages in Elementary School Children as Revealed by a Large-Scale Study Using fNIRS Reviewed International journal

    Lisa Sugiura, Shiro Ojima, Hiroko Matsuba-Kurita, Ippeita Dan, Daisuke Tsuzuki, Takusige Katura, Hiroko Hagiwara

    CEREBRAL CORTEX   21 ( 10 )   2374 - 2393   2011.10

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    DOI： 10.1093/cercor/bhr023

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  • Effects of environmental context on temporal perception bias in apparent motion Reviewed International journal

    Tomohiro Masuda, Atsushi Kimura, Ippeita Dan, Yuji Wada

    VISION RESEARCH   51 ( 15 )   1728 - 1740   2011.8

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    DOI： 10.1016/j.visres.2011.05.016

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  • Conjoint Analysis on the Purchase Intent for Traditional Fermented Soy Product (Natto) among Japanese Housewives Reviewed International journal

    Atsushi Kimura, Shigetaka Kuwazawa, Yuji Wada, Yasushi Kyutoku, Masako Okamoto, Yui Yamaguchi, Tomohiro Masuda, Ippeita Dan

    JOURNAL OF FOOD SCIENCE   76 ( 3 )   S217 - S224   2011.4

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    DOI： 10.1111/j.1750-3841.2011.02047.x

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  • Monitoring cortical hemodynamic changes after sumatriptan injection during migraine attack by near-infrared spectroscopy Reviewed International journal

    Yuka Watanabe, Hideaki Tanaka, Ippeita Dan, Kunihiko Sakurai, Kazuhito Kimoto, Ryotaro Takashima, Koichi Hirata

    NEUROSCIENCE RESEARCH   69 ( 1 )   60 - 66   2011.1

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    DOI： 10.1016/j.neures.2010.09.003

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  • Process-specific prefrontal contributions to episodic encoding and retrieval of tastes: A functional NIRS study Reviewed International journal

    Masako Okamoto, Yuji Wada, Yui Yamaguchi, Yasushi Kyutoku, Lester Clowney, Archana K. Singh, Ippeita Dan

    NEUROIMAGE   54 ( 2 )   1578 - 1588   2011.1

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    DOI： 10.1016/j.neuroimage.2010.08.016

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  • Lin4Neuro: a customized Linux distribution ready for neuroimaging analysis Reviewed International journal

    Kiyotaka Nemoto, Ippeita Dan, Christopher Rorden, Takashi Ohnishi, Daisuke Tsuzuki, Masako Okamoto, Fumio Yamashita, Takashi Asada

    BMC MEDICAL IMAGING   11   3 - 3   2011

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    DOI： 10.1186/1471-2342-11-3

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  • Eating habits in childhood relate to preference for traditional diets among young Japanese Reviewed

    Atsushi Kimura, Yuji Wada, Kentaro Ohshima, Yui Yamaguchi, Daisuke Tsuzuki, Takashi Oka, Ippeita Dan

    FOOD QUALITY AND PREFERENCE   21 ( 7 )   843 - 848   2010.10

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    DOI： 10.1016/j.foodqual.2010.05.002

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  • Package images modulate flavor perception for orange juice Reviewed

    Nanami Mizutani, Masako Okamoto, Yui Yamaguchi, Yuko Kusakabe, Ippeita Dan, Toshimasa Yamanaka

    FOOD QUALITY AND PREFERENCE   21 ( 7 )   867 - 872   2010.10

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    DOI： 10.1016/j.foodqual.2010.05.010

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  • Interactive effects of carbon footprint information and its accessibility on value and subjective qualities of food products Reviewed International journal

    Atsushi Kimura, Yuji Wada, Akiko Kamada, Tomohiro Masuda, Masako Okamoto, Sho-ichi Goto, Daisuke Tsuzuki, Dongsheng Cai, Takashi Oka, Ippeita Dan

    APPETITE   55 ( 2 )   271 - 278   2010.10

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    DOI： 10.1016/j.appet.2010.06.013

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  • Probabilistic and virtual registration for fNIRS data in action Reviewed

    Dan I, Tsuzuki D, Enkhtur L

    Clinical Neurophysiology   121 ( 7 )   2010.7

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  • Acute moderate exercise elicits increased dorsolateral prefrontal activation and improves cognitive performance with Stroop test Reviewed International journal

    Hiroki Yanagisawa, Ippeita Dan, Daisuke Tsuzuki, Morimasa Kato, Masako Okamoto, Yasushi Kyutoku, Hideaki Soya

    NEUROIMAGE   50 ( 4 )   1702 - 1710   2010.5

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    DOI： 10.1016/j.neuroimage.2009.12.023

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  • Influence of luminance distribution on the appetizingly fresh appearance of cabbage. Reviewed International journal

    Yuji Wada, Carlos Arce-Lopera, Tomohiro Masuda, Atsushi Kimura, Ippeita Dan, Sho-ichi Goto, Daisuke Tsuzuki, Katsunori Okajima

    Appetite   54 ( 2 )   363 - 8   2010.4

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    We investigated the effect that the parameters of luminance distribution in fresh food have on our visual perception of its freshness. We took pictures of the degradation over 32 h in freshness of a cabbage. We used original images, which were patches of the pictures taken at different sampling hours, and artificially generated pictures, called "matched images," created by fitting the luminance histogram shape of the original image (taken at the 1st hour) to those at various freshness stages using a luminance histogram-matching algorithm. Nine participants rated the perceived freshness of the original and the matched images on a scale of degradation. As a result, we found that the participants could quantitatively estimate the degradation in freshness of the cabbage simply by looking at the presented images. Some parameters of the luminance histograms monotonically change with decreasing freshness, indicating that the freshness of cabbage can be estimated using these parameters. However, the freshness ratings for the matched images after the 8th hour of degradation had lower modification than those for the respective original images. These results suggest that the luminance distribution in the vegetable texture partly contributes to visual freshness perception but other variables, such as spatial patterns, might also be important for estimating visual freshness.

    DOI： 10.1016/j.appet.2010.01.002

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  • Infants' recognition of objects using canonical color Reviewed International journal

    Atsushi Kimura, Yuji Wada, Jiale Yang, Yumiko Otsuka, Ippeita Dan, Tomohiro Masuda, So Kanazawa, Masami K. Yamaguchi

    JOURNAL OF EXPERIMENTAL CHILD PSYCHOLOGY   105 ( 3 )   256 - 263   2010.3

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    DOI： 10.1016/j.jecp.2009.11.002

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  • Anatomical atlas-guided diffuse optical tomography of brain activation Reviewed International journal

    Anna Custo, David A. Boas, Daisuke Tsuzuki, Ippeita Dan, Rickson Mesquita, Bruce Fischl, W. Eric L. Grimson, Williams Wells

    NEUROIMAGE   49 ( 1 )   561 - 567   2010.1

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    DOI： 10.1016/j.neuroimage.2009.07.033

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  • Effect of duration of acute moderate exercise on exericse-elicited cortical activation and cognitive performance on Stroop task: a preliminary examination Reviewed

    Hiroki Yanagisawa, Ippeita Dan, Hideaki Soya

    International Journal of Human Movement Science   3 ( 2 )   111 - 132   2009.12

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  • Structural atlas-based spatial registration for functional near-infrared spectroscopy enabling inter-study data integration Reviewed International journal

    Masako Okamoto, Daisuke Tsuzuki, Lester Clowney, Haruka Dan, Archana K. Singh, Ippeita Dan

    CLINICAL NEUROPHYSIOLOGY   120 ( 7 )   1320 - 1328   2009.7

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    DOI： 10.1016/j.clinph.2009.01.023

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  • Implicit gender-based food stereotypes. Semantic priming experiments on young Japanese Reviewed International journal

    Atsushi Kimura, Yuji Wada, Sho-ichi Goto, Daisuke Tsuzuki, Dongsheng Cai, Takashi Oka, Ippeita Dan

    APPETITE   52 ( 2 )   521 - 524   2009.4

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    DOI： 10.1016/j.appet.2008.11.002

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  • Influences of Food-Name Labels on Perceived Tastes Reviewed International journal

    Masako Okamoto, Yuji Wada, Yui Yamaguchi, Atsushi Kimura, Haruka Dan, Tomohiro Masuda, Archana K. Singh, Lester Clowney, Ippeita Dan

    CHEMICAL SENSES   34 ( 3 )   187 - 194   2009.3

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    DOI： 10.1093/chemse/bjn075

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  • Sound enhances detection of visual target during infancy: A study using illusory contours Reviewed International journal

    Yuji Wada, Nobu Shirai, Yumiko Otsuka, Akira Midorikawa, So Kanazawa, Ippeita Dan, Masami K. Yamaguchi

    JOURNAL OF EXPERIMENTAL CHILD PSYCHOLOGY   102 ( 3 )   315 - 322   2009.3

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    DOI： 10.1016/j.jecp.2008.07.002

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  • Activation in ventro-lateral prefrontal cortex during the act of tasting: An fNIRS study Reviewed International journal

    Masako Okamoto, Haruka Dan, Lester Clowney, Yui Yamaguchi, Ippeita Dan

    NEUROSCIENCE LETTERS   451 ( 2 )   129 - 133   2009.2

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    DOI： 10.1016/j.neulet.2008.12.016

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  • Prefrontal Activation Associated with Social Attachment: Facial-Emotion Recognition in Mothers and Infants Reviewed International journal

    Yasuyo Minagawa-Kawai, Sunao Matsuoka, Ippeita Dan, Nozomi Naoi, Katsuki Nakamura, Shozo Kojima

    CEREBRAL CORTEX   19 ( 2 )   284 - 292   2009.2

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    DOI： 10.1093/cercor/bhn081

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  • Consumer valuation of packaged foods. Interactive effects of amount and accessibility of information Reviewed International journal

    Atsushi Kimura, Yuji Wada, Daisuke Tsuzuki, Sho-ichi Goto, Dongsheng Cai, Ippeita Dan

    APPETITE   51 ( 3 )   628 - 634   2008.11

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    DOI： 10.1016/j.appet.2008.05.054

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  • SCOPE OF RESAMPLING-BASED TESTS IN fNIRS NEUROIMAGING DATA ANALYSIS Reviewed

    Archana K. Singh, Lester Clowney, Masakc Okamoto, James B. Cole, Ippeita Dan

    STATISTICA SINICA   18 ( 4 )   1519 - 1534   2008.10

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  • p21 activated kinase 5 activates Raf-1 and targets it to mitochondria Reviewed International journal

    Xiaochong Wu, Heather S. Carr, Ippeita Dan, Peter P. Ruvolo, Jeffrey A. Frost

    JOURNAL OF CELLULAR BIOCHEMISTRY   105 ( 1 )   167 - 175   2008.9

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    DOI： 10.1002/jcb.21809

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  • Fast (100-175 ms) components elicited bilaterally by language production as measured by three-wavelength optical imaging Reviewed International journal

    Mikio Kubota, Mayako Inouchi, Ippeita Dan, Daisuke Tsuzuki, Akihiro Ishikawa, Thomas Scovel

    BRAIN RESEARCH   1226   124 - 133   2008.8

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    DOI： 10.1016/j.brainres.2008.05.079

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  • Differential activation of frontal and parietal regions during visual word recognition: An optical topography study Reviewed International journal

    Markus J. Hofmann, Martin J. Herrmann, Ippeita Dan, Hellmuth Obrig, Markus Conrad, Lars Kuchinke, Arthur M. Jacobs, Andreas J. Fallgatter

    NEUROIMAGE   40 ( 3 )   1340 - 1349   2008.4

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    DOI： 10.1016/j.neuroimage.2007.12.037

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  • Effect of illusory thermal sensation on hardness perception Reviewed

    Wada Y, Tsuzuki D, Kaoru K, Dan I

    Japanese Journal of Psychonomic Science   27 ( 1 )   117 - 118   2008

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    We examined whether simultaneous illusory thermal sensations can influence the perception of hardness. By applying thermal stimuli on the index and ring fingers, we elicited referred thermal sensation on the middle finger, to which only hardness stimuli was applied without affecting the thermal properties of the peripheral receptors. Seven participants underwent a two-alternative forced-choice task on the perceived hardness of rubber pieces with various hardness values. The results show that the participants found samples to be harder under the cold condition. This phenomenon implies that the illusory thermal experience induces a tactile illusion in which warm (cold) material is perceived to be soft (hard).

    DOI： 10.14947/psychono.KJ00005084888

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  • First bite for hardness judgment as haptic exploratory procedure Reviewed International journal

    Haruka Dan, Masako Okamoto, Yuji Wada, Ippeita Dan, Kaoru Kohyama

    PHYSIOLOGY & BEHAVIOR   92 ( 4 )   601 - 610   2007.11

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    DOI： 10.1016/j.physbeh.2007.05.006

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  • Language activities of the brain during the recovery phase of aphasia measured with optical topography Reviewed

    Watanabe E, Maki A, Dan I

    Proceeding of IEEE/ICME International Conference on Complex Medical Engineering, 2007. CME 2007   953 - 956   2007.5

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    DOI： 10.1109/ICCME.2007.4381881

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  • Functional near-infrared spectroscopy for human brain mapping of taste-related cognitive functions Reviewed

    Masako Okamoto, Ippeita Dan

    JOURNAL OF BIOSCIENCE AND BIOENGINEERING   103 ( 3 )   207 - 215   2007.3

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    DOI： 10.1263/jbb.103.207

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  • Spatial registration of functional NIRS data to the standard stereotactic brain coordinate system.

    Dan I, Okamoto M, Tsuzuki D, Singh AK

    Recent Advances and Research Updates   8 ( 1 )   145 - 160   2007.1

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  • Exploring the false discovery rate in multichannel NIRS Reviewed International journal

    Archana K. Singh, Ippeita Dan

    NEUROIMAGE   33 ( 2 )   542 - 549   2006.11

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    DOI： 10.1016/j.neuroimage.2006.06.047

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  • Prefrontal activity during flavor difference test: Application of functional near-infrared spectroscopy to sensory evaluation studies Reviewed International journal

    Masako Okamoto, Haruka Dan, Archana K. Singh, Fumiyo Hayakawa, Valer Jurcak, Tateo Suzuki, Kaoru Kohyama, Ippeita Dan

    APPETITE   47 ( 2 )   220 - 232   2006.9

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    DOI： 10.1016/j.appet.2006.04.003

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  • Prefrontal activity during taste encoding: An fNIRS study Reviewed International journal

    Masako Okamoto, Mari Matsunami, Haruka Dan, Tomoko Kohata, Kaoru Kohyama, Ippeita Dan

    NEUROIMAGE   31 ( 2 )   796 - 806   2006.6

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    DOI： 10.1016/j.neuroimage.2005.12.021

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  • Virtual 10-20 measurement on MR images for inter-modal linking of transcranial and tomographic neuroimaging methods. Reviewed International journal

    Valer Jurcak, Masako Okamoto, Archana Singh, Ippeita Dan

    NeuroImage   26 ( 4 )   1184 - 92   2005.7

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    It is important to create a link between stereotaxic coordinates and head-surface-based positioning systems in order to share data between tomographic and transcranial brain mapping studies. In our previous studies, we established the probabilistic correspondence of the international 10-20 positions to the standard stereotaxic coordinate systems and made a reference database. However, its expansion required the physical marking of the 10-20 positions and the subsequent acquisition of MR images. To avoid such tedious procedures, we developed a virtual 10-20 measurement algorithm that can be applied to re-analyze any structural MR image that covers the whole head. As in the physical 10-20 measurements, with the reference points given, the algorithm automatically determines each 10-20 position step by step. Using the virtual 10-20 measurement method, we re-analyzed the MR images of 17 healthy subjects for whom we had determined 10-20 positions by physical marking in our previous study. The acquired 10-20 positions were normalized to the Montreal Neurological Institute (MNI) stereotactic coordinates and compared with the positions previously determined by physical measurements. 10-20 positions determined using the virtual and physical methods were roughly consistent. Average standard deviations for virtual and physical methods were 7.7 mm and 9.0 mm, respectively. There was a systematic shift in the virtual method, likely due to the absence of hair interference. We corrected the shift with affine transformation. The virtual 10-20 measurement method proved to be an effective alternative to physical marking. This method will serve as an essential tool for expanding the reference database and will further strengthen the link between tomographic and transcranial brain mapping methods.

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  • Automated cortical projection of head-surface locations for transcranial functional brain mapping. Reviewed International journal

    Masako Okamoto, Ippeita Dan

    NeuroImage   26 ( 1 )   18 - 28   2005.5

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    Recent advancements in two noninvasive transcranial neuroimaging techniques, near-infrared spectroscopy (NIRS) and transcranial magnetic stimulation (TMS), signify the increasing importance of establishing structural compatibility between transcranial methods and conventional tomographic methods, such as functional magnetic resonance imaging (fMRI) and positron emission tomography (PET). The transcranial data obtained from the head surface should be projected onto the cortical surface to present the transcranial brain-mapping data on the same platform as tomographic methods. Thus, we developed two transcranial projection algorithms that project given head-surface points onto the cortical surface in structural images, and computer programs based on them. The convex-hull algorithm features geometric handling of the cortical surface, while the balloon-inflation algorithm is faster, and better reflects the local cortical structure. The automatic cortical projection methods proved to be as effective as the manual projection method described in our previous study. These methods achieved perfect correspondence between any given point on the head surface or a related nearby point in space, and its cortical projection point. Moreover, we developed a neighbor-reference method that enables transcranial cortical projection of a given head-surface point in reference to three neighboring points and one additional standard point, even when no structural image of the subject is available. We also calculated an error factor associated with these probabilistic estimations. The current study presents a close topological link between transcranial and tomographic brain-mapping modalities, which could contribute to inter-modal data standardization.

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  • Signaling by the kinase MINK is essential in the negative selection of autoreactive thymocytes. Reviewed International journal

    Nami McCarty, Silke Paust, Koichi Ikizawa, Ippeita Dan, Xiaoyan Li, Harvey Cantor

    Nature immunology   6 ( 1 )   65 - 72   2005.1

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    Signaling through the T cell antigen receptor leading to elimination (negative selection) or differentiation (positive selection) of developing thymocytes generates a self-tolerant T cell repertoire. Here we report that the serine-threonine kinase MINK selectively connects the T cell receptor to a signaling pathway that mediates negative but not positive selection. Analysis of this pathway suggested that the essential function of MINK in the elimination of self-reactive thymocytes may be associated with 'downstream' activation of Jun kinase and enhancement of expression of the proapoptotic molecule Bim.

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  • Multimodal assessment of cortical activation during apple peeling by NIRS and fMRI. Reviewed International journal

    Masako Okamoto, Haruka Dan, Koji Shimizu, Kazuhiro Takeo, Takashi Amita, Ichiro Oda, Ikuo Konishi, Kuniko Sakamoto, Seiichiro Isobe, Tateo Suzuki, Kaoru Kohyama, Ippeita Dan

    NeuroImage   21 ( 4 )   1275 - 88   2004.4

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    An intriguing application of neuroimaging is directly measuring actual human brain activities during daily living. To this end, we investigated cortical activation patterns during apple peeling. We first conducted a pilot study to assess the activation pattern of the whole lateral cortical surface during apple peeling by multichannel near-infrared spectroscopy (NIRS) and detected substantial activation in the prefrontal region in addition to expected activations extending over the motor, premotor and supplementary motor areas. We next examined cortical activation during mock apple peeling by simultaneous measurement using multichannel NIRS and functional magnetic resonance imaging (fMRI) in four subjects. We detected activations extending over the motor, premotor and supplementary motor areas, but not in the prefrontal cortex. Thus, we finally focused on the prefrontal cortex and examined its activation during apple peeling in 12 subjects using a multichannel NIRS. We subsequently found that regional concentrations of oxygenated hemoglobin significantly increased in the measured region, which encompassed portions of the dorsolateral, ventrolateral and frontopolar areas of the prefrontal cortex. The current study demonstrated that apple peeling as practiced in daily life recruited the prefrontal cortex but that such activation might not be detected for less laborious mock apple peeling that can be performed in an fMRI environment. We suggest the importance of cortical study of an everyday task as it is but not as a simplified form; we also suggest the validity of NIRS for this purpose. Studies on everyday tasks may serve as stepping stone toward understanding human activities in terms of cortical activations.

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  • Effects of textural changes in cooked apples on the human bite, and instrumental tests Reviewed

    Haruka Dan, Hirotaka Watanabe, Ippeita Dan, Kaoru Kohyama

    Journal of Texture Studies   34 ( 5-6 )   499 - 514   2003.12

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    DOI： 10.1111/j.1745-4603.2003.tb01078.x

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  • Overlapping of MINK and CHRNE gene loci in the course of mammalian evolution. Reviewed International journal

    Ippeita Dan, Norinobu M Watanabe, Eriko Kajikawa, Takafumi Ishida, Akhilesh Pandey, Akihiro Kusumi

    Nucleic acids research   30 ( 13 )   2906 - 10   2002.7

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    Overlapping of genes, especially in an anti-parallel fashion, is quite rare in eukaryotic genomes. We have found a rare instance of exon overlapping involving CHRNE and MINK gene loci on chromosome 17 in humans. CHRNE codes for the epsilon subunit of the nicotinic acetylcholine receptor (AChRepsilon) whereas MINK encodes a serine/threonine kinase belonging to the GCK family. To elucidate the evolutionary trail of this gene overlapping event, we examined the genomes of a number of primates and found that mutations in the polyadenylation signal of the CHRNE gene in early hominoids led to the overlap. Upon extending this analysis to genomes of other orders of placental mammals, we observed that the overlapping occurred at least three times independently during the course of mammalian evolution. Because CHRNE and MINK are differentially expressed, the potentially hazardous mutations responsible for the exon overlap seem to have escaped evolutionary pressures by differential temporo-spatial expression of the two genes.

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  • Cloning and characterization of PAK5, a novel member of mammalian p21-activated kinase-II subfamily that is predominantly expressed in brain Reviewed International journal

    Akhilesh Pandey, Ippeita Dan, Troels Z. Kristiansen, Norinobu M. Watanabe, Jesper Voldby, Eriko Kajikawa, Roya Khosravi-Far, Blagoy Blagoev, Matthias Mann

    Oncogene   21 ( 24 )   3939 - 3948   2002.5

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    DOI： 10.1038/sj.onc.1205478

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  • Cloning of MASK, a novel member of the mammalian germinal center kinase III subfamily, with apoptosis-inducing properties Reviewed International journal

    Ippeita Dan, Shao En Ong, Norinobu M. Watanabe, Blagoy Blagoev, Mogens M. Nielsen, Eriko Kajikawa, Troels Z. Kristiansen, Matthias Mann, Akhilesh Pandey

    Journal of Biological Chemistry   277 ( 8 )   5929 - 5939   2002.2

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    DOI： 10.1074/jbc.M110882200

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  • Synthesis and characterization of pH/temperature-sensitive hydrogels based on chitosan derivative

    Akhilesh Pandey, Ippeita Dan, Troels Z. Kristiansen, Norinobu M. Watanabe, Jesper Voldby, Eriko Kajikawa, Roya Khosravi-Far, Blagoy Blagoev, Matthias Mann

    Polymer Bulletin   47 ( 5 )   451 - 456   2002

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    DOI： 10.1007/s002890200008

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  • Molecular cloning of MINK, a novel member of mammalian GCK family kinases, which is up-regulated during postnatal mouse cerebral development Reviewed

    Ippeita Dan, Norinobu M. Watanabe, Takeshi Kobayashi, Kaoru Yamashita-Suzuki, Yukiko Fukagaya, Eriko Kajikawa, Wataru K. Kimura, Takashi M. Nakashima, Kunihiro Matsumoto, Jun Ninomiya-Tsuji, Akihiro Kusumi

    FEBS Letters   469 ( 1 )   19 - 23   2000.3

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    DOI： 10.1016/S0014-5793(00)01247-3

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Books

  • 味わいの認知科学: |rn|舌の先から脳の向こうまで

    和田有史, 日下部裕子（ Role： Joint author食と脳機能）

    勁草書房  2011.10 

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  • International Handbook of Behavior, Diet and Nutrition

    Preedy VR ed（ Role： Joint authorChapter 140: Gender-based food stereotypes among young Japanese）

    Springer  2011.8 

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    Responsible for pages：2201-2216   Language：English   Book type：Scholarly book

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  • 精神疾患とNIRS

    福田正人（ Role： Joint authorNIRSチャンネルと標準脳）

    中山書店  2009.5 

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    Responsible for pages：66-78   Language：Japanese   Book type：Scholarly book

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  • 脳科学と芸術

    小泉英明（ Role： Joint author料理するサルと脳の進化）

    工作舎  2008.11 

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    Responsible for pages：262-266   Language：Japanese   Book type：Scholarly book

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  • 食品技術総合辞典

    林徹 編（ Role： Joint author味覚の脳機能イメージング）

    朝倉書店  2008.7 

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    Responsible for pages：134-139   Language：Japanese   Book type：Scholarly book

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  • 理工系バイオ系|rn|失敗しない大学院進学ガイド

    榎木英介, 片木りゅうじ, 檀一平太, 林衛 編著（ Role： Joint editor約１／３）

    日本評論社  2006.11 

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MISC

  • Neural Bases of Executive Function in ADHD Children as Assessed Using fNIRS Reviewed

    Takahiro Ikeda, Akari Inoue, Masako Nagashima-Kawada, Tatsuya Tokuda, Takanori Yamagata, Ippeita Dan, Yukifumi Monden

    Frontiers in Clinical Drug Research - CNS and Neurological Disorders   10   188 - 225   2022.4

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  • 光トポグラフィー検査を用いたADHDに対するグアンファシン(GXR)の脳機能学的薬理作用の可視化

    池田 尚広, 門田 行史, 井上 あかり, ストコ・ステファニー, 徳田 竜也, 橋本 珠緒, 田中 大輔, 牧 敦, 山形 崇倫, 檀 一平太

    脳と発達   53 ( Suppl. )   S214 - S214   2021.5

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  • Development of Cognitive Task for Measuring Brain Activity of Adult ADHD

    徐悠香, 新岡陽光, 檀一平太, 佐藤大樹

    日本生体医工学会大会プログラム・抄録集(Web)   59th   2020

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  • Neuroscience and Psychology: functional near-infrared spectroscopy (fNIRS) studies from experimental and clinical perspectives

    Hitachi, Ltd., Shimada Sotaro, Minagawa Yasuyo, Kobayashi Megumi, Monden Yukifumi, Yamaguchi K.Masami, Dan Ippeita

    The Proceedings of the Annual Convention of the Japanese Psychological Association   83   IS-007 - IS-007   2019.9

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    Language：Japanese   Publisher：The Japanese Psychological Association  

    DOI： 10.4992/pacjpa.83.0_is-007

    CiNii Research

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  • Identifying Cortical Area for Processing of Emotional Facial Expressions in ADHD Children Measured by Near-Infrared Spectroscopy

    Megumi Kobayashi, Masako Nagashima, Tatsuya Tokuda, Takahiro Ikeda, Yukifumi Monden, So Kanazawa, Masami K. Yamaguchi, Ryoichi Sakuta, Takanori Yamagata, Ippeita Dan

    I-PERCEPTION   10   169 - 169   2019.9

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    Web of Science

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  • ADHD児童における表情認知の神経基盤 近赤外分光法による検討

    小林 恵, 池田 尚広, 徳田 竜也, 長嶋 雅子, 門田 行史, 金沢 創, 山口 真美, 作田 亮一, 山形 崇倫, 檀 一平太

    日本心理学会大会発表論文集   83回   481 - 481   2019.8

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  • fNIRSによるmethylphenidateの効果判定に基づく患者個人レベルでのADHDにおけるASD併存有無の鑑別診断法(Individual classification of ADHD with and without ASD using fNIRS on effect of methylphenidate)

    Ikeda Takahiro, Monden Yukifumi, Tokuda Tatsuya, Nagashima Masako, Shimoizumi Hideo, Dan Ippeita, Yamagata Takanori

    脳と発達   51 ( Suppl. )   S223 - S223   2019.5

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  • Editorial: fNIRS in Psychological Research: Functional Neuroimaging Beyond Conventional Fields

    So Kanazawa, Ippeita Dan

    JAPANESE PSYCHOLOGICAL RESEARCH   60 ( 4 )   191 - 195   2018.10

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  • ASDの有無による薬剤療法無経験ADHDにおけるMPH誘発性血行動態応答 fNIRS研究(MPH-induced hemodynamic responses in medication-naive ADHD with and without ASD: an fNIRS study)

    Ikeda Takahiro, Monden Yukifumi, Tokuda Tatsuya, Nagashima Masako, Shimoizumi Hideo, Dan Ippeita, Yamagata Takanori

    脳と発達   50 ( Suppl. )   S285 - S285   2018.5

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  • fNIRS-Based Clinical Assessment of ADHD Children

    Yukifumi Monden, Masako Nagashima, Haruka Dan, Takahiro Ikeda, Yasushi Kyutoku, Takanori Yamagata, Ippeita Dan

    High-Resolution Neuroimaging - Basic Physical Principles and Clinical Applications   2018.3

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    Publisher：InTech  

    DOI： 10.5772/intechopen.71835

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  • fNIRSを用いた小児における発達に伴う神経活性化の変化に関する研究(A shift of neural activation with development in children, using fNIRS study)

    Ikeda Takahiro, Monden Yukifumi, Nagashima Masako, Shimoizumi Hideo, Osaka Hitoshi, Dan Ippeita, Yamagata Takanori

    脳と発達   49 ( Suppl. )   S293 - S293   2017.5

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  • A semi-learning algorithm for noise rejection: an fNIRS study on ADHD children

    Stephanie Sutoko, Tsukasa Funane, Takusige Katura, Hiroki Sato, Masashi Kiguchi, Atsushi Maki, Yukifumi Monden, Masako Nagashima, Takanori Yamagata, Ippeita Dan

    OPTICAL TOMOGRAPHY AND SPECTROSCOPY OF TISSUE XII   10059   2017

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  • 行動抑制課題中ADHD小児の個別的分類に関するfNIRSベース評価(fNIRS-based assessment of individual classification of ADHD children during an inhibition task)

    Nagashima Masako, Monden Yukifumi, Dan Ippeita, Ikeda Takahiro, Uga Minako, Shimoizumi Hideo, Yamagata Takanori

    脳と発達   48 ( Suppl. )   S237 - S237   2016.5

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  • 2種の抑制課題により可能なASDとAD/HD小児の識別(Two types of inhibition tasks allow discrimination between ASD and AD/HD children)

    Ikeda Takahiro, Monden Yukifumi, Hirai Masahiro, Nagashima Masako, Shimoizumi Hideo, Osaka Hitoshi, Dan Ippeita, Yamagata Takanori

    脳と発達   48 ( Suppl. )   S238 - S238   2016.5

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  • 抑制機能課題を用いた光トポグラフィー計測によるASD児とADHD児の鑑別のためのバイオマーカー探索

    徳田竜也, 長嶋雅子, 宇賀美奈子, 宇賀美奈子, 池田尚広, 山岸佑也, 下泉秀夫, 山形崇倫, 檀一平太, 門田行史, 門田行史, 門田行史

    日本赤ちゃん学会学術集会プログラム・要旨集   16th   2016

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  • 投薬を受けていないADHDにおけるMPH効果のfNIRSによる測定(fNIRS-based assessment of MPH effect in drug-naive ADHD: a double-blind, placebo-controlled study)

    Nagashima Masako, Monden Yukifumi, Dan Ippeita, Mizutani Tutomu, Ikeda Takahiro, Shimoizumi Hideo, Watanabe Eijyu, Yamagata Takanori

    脳と発達   47 ( Suppl. )   S211 - S211   2015.5

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  • 小児ADHDの注意機能に関する脳機能障害部位と塩酸メチルフェニデートの効果 fNIRSを用いた検討

    長嶋 雅子, 門田 行史, 檀 一平太, 檀 はるか, 水谷 勉, 郡司 勇治, 桃井 真里子, 渡辺 英寿, 山形 崇倫

    日本薬物脳波学会雑誌   15 ( 1 )   33 - 45   2014.8

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  • ADHDにおけるatomoxetineとmethylphenidateの神経機能に対する作用の違い(Differences in neurofunctional effects between atomoxetine and methylphenidate in ADHD)

    Nagashima Masako, Monden Yukifumi, Dan Ippeita, Shimoizumi Hideo, Watanabe Eijyu, Yamagata Takanori

    脳と発達   46 ( Suppl. )   S232 - S232   2014.5

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  • 注意欠陥多動性障害(ADHD)の脳機能学的検討 機能的近赤外分光法(fNIRS)を用いたADHD治療薬の効果

    門田 行史, 檀 一平太, 山形 崇倫

    脳と発達   46 ( Suppl. )   S208 - S208   2014.5

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  • fNIRS信号による言語流暢性課題における日本語特有な皮質脳活動

    佐野 俊文, 檀 はるか, 檀 一平太, 久徳 康史, 小黒 恵司, 横田 英典, 續木 大介, 渡辺 英寿

    認知神経科学   15 ( 2 )   126 - 126   2013.6

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  • ADHD小児における注意関連皮質血行動態を探索するためのMPH誘導性fNIRSモニタリング(MPH-induced fNIRS Monitoring to Explore Attention-related Cortical Hemodynamics in ADHD Children)

    Nagashima Masako, Monden Yukifumi, Dan Ippeita, Mizutani Tsutomu, Gunji Yuji, Yamagata Takanori, Watanabe Eiju, Momoi Y. Mariko

    脳と発達   45 ( Suppl. )   S220 - S220   2013.5

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  • 無治療および投薬治療を受けたADHD患者の右前頭頭頂皮質での脳活性化の比較(Comparison of Brain Activation at Right Fronto-parietal Cortex between Naive and Medicated ADHD)

    Monden Yukifumi, Dan Ippeita, Nagashima Masako, Mizutani Tsutomu, Yamagata Takanori, Watanabe Eiju, Momoi Mariko

    脳と発達   45 ( Suppl. )   S220 - S220   2013.5

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  • fNIRSを用いたADHDの実行機能解析とMPHの薬理効果の検討-小児における早期診断を目指して

    門田行史, 門田行史, 檀はるか, 檀一平太, 長嶋雅子, 續木大介, 久徳康史, 山形崇倫, 郡司勇治, 渡辺英寿, 桃井真里子

    日本薬物脳波学会雑誌   14 ( 1 )   2013

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  • 高齢期における体力レベルと前頭前野代償機能の関係

    兵頭 和樹, 檀 一平太, 諏訪部 和也, 征矢 英昭

    体力科学   61 ( 6 )   663 - 663   2012.12

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  • 発達障害と脳機能 fNIRSを用いた解析系による小児ADHDの客観的評価の確立を目指して

    長嶋 雅子, 門田 行史, 檀 はるか, 檀 一平太, 續木 大介, 久徳 康史, 山形 崇倫, 郡司 勇治, 渡辺 英寿, 桃井 真里子

    臨床神経生理学   40 ( 5 )   425 - 425   2012.10

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  • 短時間運動により高まる高齢者の高次認知機能とその脳機構 右脳の代償機能の促進

    兵頭 和樹, 檀 一平太, 諏訪部 和也, 赤堀 三哉, 山田 論基, ビョン・ギョンホ

    日本抗加齢医学会総会プログラム・抄録集   12回   185 - 185   2012.6

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  • ADHD児におけるMPH作用の臨床指向性fNIRSモニタリング(Clinically-oriented fNIRS Monitoring of MPH Effect in ADHD Children)

    Monden Yukifumi, Dan Ippeita, Nagashima Masako, Yamagata Takanori, Watanabe Eiju, Momoi Mariko

    脳と発達   44 ( Suppl. )   S188 - S188   2012.5

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  • Spatial and temporal considerations for achieving intermodal cross-referencing of fNIRS data.

    Dan I

    UK/JP Workshop for Multimodal Imaging (Kavli Center, UK, Chaired by Dan I & Tacsides I)   2012.2

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    Language：English   Publisher：The UK Embassy of Tokyo, and The Royal Society  

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  • 報告書：NIRSを用いた精神疾患の早期診断についての実用化研究 NIRSデータと脳構造の対応の確立

    檀 一平太

    平23年度 総括・分担研究報告書   44 - 51   2012

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  • [Strategy on dealing with noisy NIRS data: implications on functional neuroimaging on swallowing].

    Ippeita Dan, Toshifumi Sano, Haruka Dan, Eiju Watanabe

    Rinsho shinkeigaku = Clinical neurology   52 ( 11 )   1188 - 90   2012

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    Functional near-infrared spectroscopy (fNIRS) may be suited for functional monitoring during swallowing as it is comparatively immune to body movement. However, still fNIRS measurement on swallowing poses a technical problem that it may often involve motion artifacts. Although there is no single way to solve this problem, technical insights have been available form related studies in the past. Here we introduce two examples for analyzing data rich in motion artifacts putting emphasis on temporal structures of the data. The first is about fNIRS assessment of language function during overt naming tasks. Since data were temporally continuous, we adopted a general linear model with regression to a canonical hemodynamic response function to extract cortical activations related to overt naming tasks. The second example is about fNIRS assessment on go/no-go task performance with or without methylphenidate administration in Attention Deficit Hyperactivity Disorder (ADHD) children. Since data were disrupted by unexpected motion artifacts, we simplified temporal data structures by averaging to extract only robust signals. Thus, we indicated that the optimum analytical strategy varies depending on the temporal structures of the data.

    PubMed

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  • 小児ADHDに対するMPH投与効果のNIRSによる評価法の探索

    門田行史, 檀はるか, 長嶋雅子, 檀一平太, 久徳康史, 岡本雅子, 山形崇倫, 桃井真里子, 渡辺英寿

    日本薬物脳波学会雑誌   13 ( 1 )   2012

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  • 一過性の中強度運動は高齢者の代償機能を高め、実行機能を向上させる

    兵頭 和樹, 諏訪部 和也, 檀 一平太, 征矢 英昭

    体力科学   60 ( 6 )   585 - 585   2011.12

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  • 報告書：食​品​・​農​産​物​の​表​示​の​信​頼​性​確​保​と​機​能​性​解​析​の​た​め​の​基​盤​技​術​の​開​発​ ​ ​第​3​章​ ​ ​生​体​の​感​覚​情​報​測​定​を​応​用​し​た​機​能​性​評​価​ ​ ​3​ ​ ​食​品​及​び​そ​の​成​分​の​摂​取​形​態​が​生​体​の​脳​機​能​等​に​与​え​る​影​響​の​解​明

    河合崇行, 檀一平太

    農林水産省農林水産技術会議事務局研究成果   493,155 - 157   2011.11

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  • 「​最​近​の​脳​科​学​」​光​脳​機​能​イ​メ​ー​ジ​ン​グ​の​進​歩

    日大医学雑誌   70 ( 3 )   145 - 149   2011.10

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  • 嗅覚・味覚研究の最前線—現状と展望—ＮＩＲＳによる味嗅覚研究の現状と可能性

    檀一平太

    Foods & Food Ingredient Journal of Japan   216 ( 2 )   129 - 138   2011.5

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    Language：Japanese   Publisher：FFIジャーナル編集委員会  

    CiNii Books

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  • 近赤外線スペクトロスコピーを用いた小児注意欠陥/多動性障害に対する塩酸メチルフェニデート治療効果の検討

    門田 行史, 檀 一平太, 長嶋 雅子, 渡辺 英寿, 山形 崇倫, 桃井 真里子

    脳と発達   43 ( Suppl. )   S339 - S339   2011.5

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  • 食文化の脳内探索—おいしさを超えて—

    檀一平太

    生存科学   216 ( 2 )   129 - 138   2011.3

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  • P2-u15 The usefulness of double density optical topography

    Keiji Oguro, Hidenori Yokota, Ayano Izawa, Ippeita Dan, Eiju Watanabe

    NEUROSCIENCE RESEARCH   71   E206 - E206   2011

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    DOI： 10.1016/j.neures.2011.07.892

    Web of Science

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  • Probabilistic Spatial Registration of NIRS/OT Data with Crossmodal Perspective. In the symposium “Cut the edge of NIRS/OT technique toward synthesis for the next generation” Organized by Dan I Reviewed

    Dan I

    HBM2010 Barcelona: Annual Meeting of Organization for Human Brain Mapping (Barcelona, Spain)   2010.6

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  • 中強度運動で高まる実行機能の神経基盤—ｆＮＩＲＳを用いたニューロイメージング研究—

    征矢英昭, 柳澤弘樹, 檀一平太

    体育の科学   60 ( 4 )   242 - 249   2010.6

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  • 体育学研究へのＮＩＲＳ応用可能性－落とし穴に落ちないために

    檀一平太

    体育の科学   60 ( 4 )   221 - 227   2010.6

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  • ＮＩＲＳ脳機能計測データの空間的レジストレーション

    續木大介, 檀一平太

    JAMIT e News Letter (Web)   5   12 - 13   2010.4

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  • ロゴマークの熟知度が色のみえに及ぼす効果(日本基礎心理学会第28回大会,大会発表要旨)

    木村 敦, 和田 有史, 増田 知尋, 後藤 祥一, 續木 大介, 檀 一平太

    基礎心理学研究   28 ( 2 )   262 - 262   2010

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    Language：Japanese   Publisher：日本基礎心理学会  

    DOI： 10.14947/psychono.KJ00006393807

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  • 報告書：脳画像のもとづく精神疾患の「臨床病期」概念の確立と適切な治療・予防法の選択への応用についての研究

    平21年度 総括・分担研究報告書   48 - 4   2010

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  • Mapping of Optical Pathlength of Human Adult Head at Multi-Wavelengths in Near Infrared Spectroscopy International journal

    Akihisa Katagiri, Ippeita Dan, Daisuke Tuzuki, Masako Okamoto, Noriaki Yokose, Kouji Igarashi, Tatsuya Hoshino, Tokuo Fujiwara, Youichi Katayama, Yui Yamaguchi, Kaoru Sakatani

    OXYGEN TRANSPORT TO TISSUE XXXI   662   205 - 212   2010

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  • 論文引用動向からみる近赤外脳機能イメージング研究のエポック

    檀一平太

    放射線科学   52 ( 9 )   14 - 26   2009.10

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  • IMPULSIVITY-RELATED PREFRONTAL ACTIVATION DURING REWARD DISCOUNTING IS MODERATED BY COMT VAL158MET POLYMORPHISM

    Michael M. Plichta, Sebastian Heinzel, Antje B. M. Gerdes, Ann-Christine Ehlis, Andreas Reif, Ippeita Dan, Klaus-Peter Lesch, Georg Gron, Paul Pauli, Andreas J. Fallgatter

    PSYCHOPHYSIOLOGY   46   S151 - S151   2009.9

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    Web of Science

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  • NIRSによる味嗅覚研究の戦略的考察 Reviewed

    檀一平太

    Aroma Research   10 ( 2 )   110 - 117   2009.5

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    Language：Japanese   Publisher：フレグランスジャーナル社  

    CiNii Books

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    Other Link： http://search.jamas.or.jp/link/ui/2009243392

  • 食味のニューロイメージング

    檀一平太

    食糧   47   75 - 86   2009.4

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  • 報告書：脳画像にもとづく精神疾患の臨床病期概念の確立と適切な治療・予防法の選択への応用についての研究

    檀 一平太

    平成20年度 総括・分担研究報告書   40 - 3   2009

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  • Visual cues on food freshness perception: How luminance influences the freshness perception of vegetables

    C. A. Arce Lopera, T. Masuda, Y. Wada, I. Dan, A. Kimura, K. Okajima

    PERCEPTION   38   96 - 96   2009

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    Web of Science

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  • 視覚による鮮度知覚に光学特性が及ぼす影響(日本基礎心理学会第27回東北大会,大会発表要旨)

    和田 有史, Carlos Arce-Lopera, 増田 知尋, 木村 敦, 續木 大介, 後藤 祥一, 檀一 平太, 岡嶋 克典

    基礎心理学研究   27 ( 2 )   2009

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    DOI： 10.14947/psychono.KJ00005578274

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  • 脳機能イメージングで分かること分からぬこと

    檀一平太, 岡本雅子

    ソフト・ドリンク技術資料   156 ( 3 )   2008.12

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  • 光トポグラフィー 中強度運動後に高まるStroop成績に連関した背側前頭前野の活性化 事象関連fNIRS研究

    征矢 英昭, 桝澤 弘樹, 岡本 雅子, 檀 一平太

    臨床神経生理学   36 ( 5 )   453 - 454   2008.10

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  • Probabilistic spatial registration of fNIRS data with crossmodal perspective

    Dan I

    13th Annual Meeting of Pacific Rim College of Psychiatrists (Tokyo)   2008.10

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  • 硬さの知覚に主観的な温度が及ぼす影響(日本基礎心理学会第26回大会,大会発表要旨)

    和田 有史, 續木 大介, 神山 かおる, 檀 一平太

    基礎心理学研究   26 ( 2 )   216 - 216   2008

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    DOI： 10.14947/psychono.KJ00004902546

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  • Cerebral activation patterns during swallowing: An fNIRS study

    Masanaga Yamawaki, Masako Okamoto, Ippeita Dan, Hidehiro Mizusawa

    NEUROSCIENCE RESEARCH   61   S168 - S168   2008

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  • Bayesian statistics, frequentist statistics and fNIRS

    Lester Clowney, Archana Singh, Masakc Okamoto, Ippeita Dan

    NEUROSCIENCE RESEARCH   61   S213 - S213   2008

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  • Prefrontal involvement in taste recognition: fNRIS study

    Masako Okamoto, Yuji Wada, Daisuke Tsuzuki, Lester Clowney, Archana Singh, Ippeita Dan

    NEUROSCIENCE RESEARCH   61   S248 - S248   2008

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  • Resampling fNIRS time series in wavelet domain

    Archana K. Singh, Masako Okamoto, Clowney Lester, James B. Cole, Dan Ippeita

    NEUROSCIENCE RESEARCH   61   S278 - S278   2008

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  • 光トポグラフィ臨床応用のための空間的標準化 Reviewed

    檀一平太

    認知神経科学   9 ( 1 )   13 - 18   2007.12

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  • 脳科学は官能評価に何をもたらすか

    檀一平太, 岡本雅子

    食品工業   51 ( 2 )   27 - 33   2007.12

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    J-GLOBAL

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  • 味の記憶とヒトの脳

    檀一平太, 岡本雅子

    Bioindustry   24 ( 12 )   87 - 94   2007.12

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    CiNii Books

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  • 脳機能イメージング法による味覚研究

    檀一平太, 岡本雅子

    フードケミカル   2007 ( 12 )   38 - 45   2007.12

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  • 光トポグラフィ臨床応用のための空間的標準化 (第12回認知神経科学会) -- (シンポジウム 光脳機能計測の臨床応用)

    檀 一平太

    認知神経科学   9 ( 3 )   207 - 213   2007.12

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    Other Link： http://search.jamas.or.jp/link/ui/2008159232

  • 一過性の中等度運動により高まる認知機能は関連脳部位の活性化を伴うか? fNIRSによる局所血流応答の解析から

    柳澤 弘樹, 西島 壮, 岡本 雅子, 檀 一平太, 征矢 英昭

    体力科学   56 ( 6 )   583 - 583   2007.12

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  • 光による味の脳機能マッピング Reviewed

    岡本雅子, 檀一平太

    日本味と匂学会誌   14 ( 2 )   193 - 198   2007.8

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    Other Link： http://search.jamas.or.jp/link/ui/2008064685

  • 近赤外光による脳機能解析法fNIRS－方法論の発展と課題 Reviewed

    檀一平太

    ぶんせき   2007 ( 6 )   276 - 283   2007.6

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    Other Link： http://search.jamas.or.jp/link/ui/2008047882

  • 光トポグラフィデータの空間的レジストレーション Reviewed

    檀一平太

    認知神経科学   9 ( 1 )   13 - 18   2007.4

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    DOI： 10.11253/ninchishinkeikagaku1999.9.13

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  • Prefrontal activity during intentional encoding of taste: fNIRS study

    M. Okamoto, M. Matsunami, H. Dan, T. Kohata, K. Kohyama, I. Dan

    CHEMICAL SENSES   32 ( 2 )   J13 - J13   2007.2

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  • Aesthetics in gustation: Insight from recent neuroimaging studies

    Ippeita Dan

    NEUROSCIENCE RESEARCH   58   S23 - S23   2007

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    DOI： 10.1016/j.neures.2007.06.135

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  • Non-parametric resampling-based methods for functional NIRS studies

    Archana K. Singh, Masako Okamoto, James B. Cole, Ippeita Dan

    NEUROSCIENCE RESEARCH   58   S243 - S243   2007

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    DOI： 10.1016/j.neures.2007.06.602

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  • Ventrolateral prefrontal response to taste stimuli

    Masako Okamoto, Yuji Wada, Daisuke Tsuzuki, Archana Singh, Ippeita Dan

    NEUROSCIENCE RESEARCH   58   S233 - S233   2007

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    DOI： 10.1016/j.neures.2007.06.540

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  • Optical topography

    Ippeita Dan

    JOURNAL OF THE JAPANESE SOCIETY FOR FOOD SCIENCE AND TECHNOLOGY-NIPPON SHOKUHIN KAGAKU KOGAKU KAISHI   54 ( 8 )   383 - 383   2007

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  • Toward standardizing spatial analysis for optical topography

    Ippeita Dan, Masako Okamoto, Daisuke Tsuzuki, Archana K. Singh

    2007 IEEE/ICME INTERNATIONAL CONFERENCE ON COMPLEX MEDICAL ENGINEERING, VOLS 1-4   2012 - 2018   2007

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  • Prefrontal activity during intentional encoding of taste : fNIRS study

    OKAMOTO Masako, MATSUNAMI Mari, DAN Haruka, KOHATA Tomoko, KOHYAMA Kaoru, DAN Ippeita

    The Japanese journal of taste and smell research   13 ( 3 )   459 - 460   2006.12

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  • 大学教授のためのバイオ物理入門 赤外線で心は透けるか？（後編）

    檀一平太

    Baionics   2006 ( 5 )   54 - 56   2006.5

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  • 大学教授のためのバイオ物理入門 赤外線で心は透けるか？（前編）

    檀一平太

    Baionics   2006 ( 4 )   66 - 68   2006.4

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  • 公開情報：効率的な消費者の情報理解のための情報提示方法

    和田有史

    食品研究成果情報   23,6 - 7   2006.3

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  • 公開情報：脳における味の記憶生成の可視化

    檀一平太

    食品研究成果情報   ( 18 )   18,20 - 1   2006.3

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    J-GLOBAL

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  • Human prefrontal activity in taste encoding: An fNIRS study

    Masako Okamoto, Mari Matsunami, Haruka Dan, Tomoko Kohata, Kaoru Kohyamal, Ippeita Dan

    NEUROSCIENCE RESEARCH   55   S249 - S249   2006

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  • Spatial registration of stand-alone fNIRS data to MNI space

    Ippeita Dan, Archana Singh, Masako Okamoto

    NEUROSCIENCE RESEARCH   55   S72 - S72   2006

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  • 食生活研究への適用のためのｆＮＩＲＳ単独での脳機能マッピング法開発

    檀一平太

    食品総合研究所研究ニュース   13   4 - 5   2005.7

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  • 日本の科学の生きる道－自ら道を切り拓けるか？

    檀一平太

    蛋白質酵素核酸   2003 ( 11 )   2003.11

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  • 日本の科学の生きる道－対処療法によるポスドク問題解決

    檀一平太

    蛋白質酵素核酸   2003 ( 10 )   2003.10

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  • 日本の科学の生きる道－田中さん的研究者育成によるポスドク問題解決

    檀一平太

    蛋白質酵素核酸   2003 ( 9 )   2003.9

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  • 新聞：私の視点、研究者育成、若手が自立できる支援を

    檀一平太

    朝日新聞   2003.6

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  • Japanese system buries the individual researcher. International journal

    Ippeita Dan

    Nature   423 ( 6937 )   221 - 221   2003.5

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    PubMed

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  • 大脳神経回路網形成に関与する遺伝子群の検索：Poly(A)+ mRNA fingerprinting by arbitrary primers (PRAP)法による試み Reviewed

    檀一平太

    物性研究   68 ( 1 )   64 - 78   1997.4

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    Other Link： http://dl.ndl.go.jp/info:ndljp/pid/10938441

▼display all

Presentations

  • 高齢期における体力レベルと前頭前野代償機能の関係

    兵頭和樹

    2012.12 

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  • fNIRSを用いた解析系による小児ADHDの客観的評価の確立を目指して

    長嶋雅子

    2012.10 

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  • ミニブタの脳におけるframless stereotaxyの検証

    齋藤敏之

    2012.8 

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  • 従来型および倍密度光トポグラフィーのてんかん焦点診断への応用

    エジソン リゼキ・エドミ

    2012.6 

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  • 倍密度光トポグラフィーへの挑戦

    小黒恵司

    2012.6 

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  • 倍密度光トポグラフィーの臨床応用

    小黒恵司

    2012.1 

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  • 短時間運動により高まる高齢者の高次認知機能とその脳機構:右脳の代償機能の促進

    兵頭和樹

    2012 

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  • 日本における片頭痛患者の気質性格調査

    檀一平太

    2012 

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  • NIRS脳機能計測におけるノイズとの戦い:嚥下研究応用への示唆

    檀一平太

    2012 

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  • 一過性の中強度運動は高齢者の代償機能を高め,実行機能を向上させる

    兵頭和樹

    2011.12 

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  • 倍解像度ＮＩＢＳ測定と独立成分分析による信号源解析

    佐​野​俊​文, 檀​一​平

    2011.11 

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  • The clinical usefulness of double density optical topography

    Oguro K

    2011.9 

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  • 脳磁図による下歯槽神経機能障害の客観的評価

    佐瀬美和

    2011.9 

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  • 倍密度光トポグラフィーへの挑戦

    小黒恵司

    2011.9 

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  • 呼称課題の発声有無に伴う脳活動パターンの光トポグラフィーによる検討

    檀はるか

    2011.9 

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  • セ​ロ​ト​ニ​ン​受​容​体​選​択​的​作​動​薬​を​用​い​た​脳​血​液​量​評​価​—​片​頭​痛​患​者​で​の​検​討​結​果​か​ら​—

    渡​邉​由

    2011.5 

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  • 光​ト​ポ​グ​ラ​フ​ィ​ー​に​よ​る​失​語​症​回​復​過​程​の​計​測

    盛合彩乃

    2011.5 

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  • 美味しさの評価系の構築と応用

    中野久美

    2011.3 

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  • 光​ト​ポ​グ​ラ​フ​ィ​を​用​い​た​嚥​下​運​動​時​の​脳​活​動​部​位​の​解​析​：​座​位​と​リ​ク​ラ​イ​ニ​ン​グ​で​の​比​較

    柴野荘一

    2010.12 

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  • 軟口蓋刺激時の大脳運動感覚野の変化：アイスマッサージのメカニズムへの考察

    山脇正永

    2010.11 

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  • 失語症者における光トポグラフィーによる脳機能計測での発語下呼称課題の有用性

    盛合彩乃

    2010.10 

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  • フォトグラメトリック法によるＮＩＲＳデータのレジストレーション

    檀一平太

    2010.10 

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  • Probabilistic and virtual registration for fNIRS data in action

    Dan I, Tsuzuki D

    2010.7 

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  • 混合味の強度評定における熟練者の優位性

    増​田​知

    2010.4 

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  • ロゴマークの熟知度が色のみえに及ぼす効果

    木村敦

    2010.3 

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  • パ​ッ​ケ​ー​ジ​画​像​が​記​憶​上​の​味​の​変​容​に​及​ぼ​す​影​響

    水​谷​奈, 那

    2010 

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  • 座位時の非命令嚥下では感覚処理中枢が重要である

    山脇正永, 岡本雅子, 檀一平太

    2009.12 

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  • ｆＮＩＲＳの空間的データ解析の実演

    檀一平太

    2009.10 

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  • 近赤外線分光法を用いた片頭痛発作中患者の血流解析

    渡​邉​由

    2009.6 

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  • ＮａＣｌ溶液の強度評定における熟練者の優位性—評定値の確度と精度—

    増​田​知

    2009.4 

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  • 乳児期の多感覚知覚の発達

    和田有史

    2009.4 

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  • 視覚による鮮度知覚に光学特性が及ぼす影響

    和田有史

    2009.3 

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  • 運動知覚における加速度変化の影響

    増​田​知

    2009.3 

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  • Effects of luminance and color information on the perceived freshness of vegetables

    Ars Lopera

    2009.1 

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  • 画像解析ソフトがプリインストールされているＬｉｎｕｘディストリビューション，Ｎｅｕｂｕｎｔｕの開発

    根本清貴

    2009 

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  • 摂食に関わる脳活動

    岡本雅子, 檀一平太

    2009 

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  • 座位における嚥下運動時の脳機能活動の分析

    山脇正永

    2009 

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  • 標準頭部モデルの光伝播解析によるｆＮＩＲＳ脳機能計測における測定領域の確率的マッピング

    大木陽介

    2008.12 

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  • 中強度運動後に高まるＳｔｒｏｏｐ成績に連関した背側前頭前野の活性化：事象関連ｆＮＩＲＳ研究

    征矢英昭

    2008.10 

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  • 野菜の鮮度知覚に画像特性が及ぼす影響

    カルロス・アルセロペラ

    2008.8 

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  • 食品ブランドの認知度と記憶色

    2008.5 

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  • 味再認中のパネルの脳活動：ｆＮＩＲＳ研究

    岡本雅子

    2008.4 

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  • 食に関するイメージと非言語情報：食表現語の評定と抽象図形の生成

    山口由衣, 和田有史, 檀一平太

    2008.4 

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  • 主観的温度による硬さの錯覚

    和田有史

    2008.4 

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  • 視覚的テクスチャーが果物の鮮度知覚に及ぼす影響

    木村敦

    2008.4 

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  • Cerebral activation patterns during swallowing: An fNIRS study

    Yamawaki

    2008 

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  • Prefrontal involvement in taste recognition: fNRIS study

    Okamoto M

    2008 

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  • Bayesian statistics, frequentist statistics and fNIRS

    Clowney L

    2008 

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  • 近赤外線分光法（ＮＩＲＳ）を用いた片頭痛発作時患者の脳血流解析

    渡​邉, 由

    2008 

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  • 機能的近赤外分光分析法ｆＮＩＲＳによる脳機能計測の応用と課題

    檀一平太

    2007.11 

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  • Ventrolateral prefrontal response to taste stimuli

    Okamoto M

    2007.8 

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  • Non-parametric resampling-based methods for functional NIRS studies

    Singh AK

    2007.8 

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  • Aesthetics in gustation: insight from recent neuroimaging studies

    Dan I

    2007.8 

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  • 手描き図形を用いた印象伝達

    山口由衣, 和田有史, 檀一平太

    2007.4 

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  • 官能評価中のパネルの脳活動：ｆＮＩＲＳ研究

    岡本雅子

    2007.4 

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  • 光トポグラフィ臨床応用のための空間的標準化

    檀一平太

    2007 

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  • 味覚の意図的記銘における前頭前野の活動：ｆＮＩＲＳ研究

    岡本雅子

    2006.12 

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  • ｆＮＩＲＳによる味記銘中の前頭活動計測

    岡本雅子

    2006.7 

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  • 光脳機能計測信号の空間的レジストレーション

    檀一平太

    2006.7 

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  • Probabilistic and automated registration of transcranial functional brain mapping data onto the cortical surface

    Okamoto M, Singh A, Jurcak V, Dan I

    2005.6 

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  • Examination of lateral PFC activity in tea tasting: a Functional Near-infrared Spectroscopy Study

    Okamoto M

    2005.6 

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  • ＮＩＲＳによる脳機能解析の食品科学研究への応用‐適用例と課題

    岡本雅子

    2004.9 

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  • Exploring cortical activity during everyday tasks: Multimodal assessment of cortical activation during apple peeling by NIRS and fMRI

    Okamoto M

    2004.6 

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  • Toward three-dimensional probabilistic anatomical cranio-cerebral correlation via the international 10-20 system oriented for transcranial functional brain mappingpeeling by NIRS and fMRI

    Okamoto M

    2004.6 

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  • 新規遺伝子ＧＣＫ ｆａｍｉｌｙ ｋｉｎａｓｅ，ＭＩＮＫの生後マウス小脳における発達依存的発現

    鈴木香

    2000.9 

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  • マウス大脳の生後発達に関与する遺伝子群の解析

    檀一平太, 渡辺紀信, 楠見明弘

    1998.9 

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  • Analysis of genes that are involved in postnatal mouse cerebral development

    Dan I, Watanabe M, Kusumi A

    1998 

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  • Ｐｏｌｙ（Ａ）＋ＲＡＰ法による生後マウスの大脳神経回路網形成に関与する遺伝子郡の解析

    檀一平太, 中川雅史, 楠見明弘

    1997 

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  • ＰＲＡＰ法による大脳神経回路網形成に関与する遺伝子群の検索

    檀一平太

    1996.10 

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  • 大脳神経回路網形成に関する遺伝子群の系統的検索

    檀一平太, 引地愉香, 楠見明弘

    1995.8 

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Awards

  • Excellent Presentation Award

    2022.3  

    Ippeita Dan

  • Excellent Paper Award

    2019.8   The Japanese Psychological Association   Hypoactivation of the Right Prefrontal Cortex Underlying Motor‐Related Inhibitory Deficits in Children with Autism Spectrum Disorder: A Functional Near‐Infrared Spectroscopy Study

    Takahiro Ikeda, Tatsuya Tokuda, Yukifumi Monden, Masahiro Hirai, Sakae G. Mizushima, Masako Nagashima, Yasushi Kyutoku, Takamichi Taniguchi, Hideo Shimoizumi, Ippeita Dan

  • 食品総合研究所所長賞

    2008.11   食品総合研究所   食品研究への貢献

  • 日本官能評価学会優秀発表賞

    2007.11   日本官能評価学会   官能評価中のパネルの脳活動：fNIRS研究

    食品総合研究所岡本雅子らとの共同授賞

  • Eminent Scientist of the Year 2007

    2007.5   International Research Promotion Council   World Scientists Forum International Awards in Neuroimaging

  • 安藤百福賞発明発見奨励賞

    2006.12   食創会   fNIRS脳機能イメージングによる味覚の高次脳処理の先駆的研究

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Research Projects

  • A New Therapeutic Strategy for Pharmaceutical Dosage Forms and Drug Delivery

    Grant number：24K02780  2024.4 - 2027.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)  Tokyo Medical and Dental University

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    Grant amount： \11960000 （ Direct Cost: \9200000 、 Indirect Cost： \2760000 ）

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  • 知的才能児の認知的特性を反映するニューロバイオマーカー創出

    Grant number：24K21461  2024.6 - 2026.3

    日本学術振興会  科学研究費助成事業  挑戦的研究(萌芽)  中央大学

    檀 一平太

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    Grant amount： \6240000 （ Direct Cost: \4800000 、 Indirect Cost： \1440000 ）

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  • Toward developing a novel English educational method by visualizing English skills through fNIRS-based neuroimaging

    Grant number：23K21953  2022.4 - 2025.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)  Chuo University

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    Grant amount： \17420000 （ Direct Cost: \13400000 、 Indirect Cost： \4020000 ）

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  • Toward developing a novel English educational method by visualizing English skills through fNIRS-based neuroimaging

    Grant number：22H00681  2022.4 - 2025.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)  Chuo University

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    Grant amount： \17420000 （ Direct Cost: \13400000 、 Indirect Cost： \4020000 ）

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  • Effects of genotypes on neuropharmacological responses of ADHD children

    Grant number：22K18653  2022.6 - 2024.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Challenging Research (Exploratory)  Chuo University

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    Grant amount： \6370000 （ Direct Cost: \4900000 、 Indirect Cost： \1470000 ）

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  • 就業者の潜在的なPTEリスク群に対する一次予防効果の検証

    Grant number：21K11656  2021.4 - 2024.3

    日本学術振興会  科学研究費助成事業  基盤研究(C)  中央大学

    久徳 康史, 檀 一平太, 山科 満

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    Grant amount： \4030000 （ Direct Cost: \3100000 、 Indirect Cost： \930000 ）

    2022年度は二つの実験を実施し、介入により就業者の心理状態が向上するかを検証した。一つ目の実験に関しては、アルバイト就業者、もしくはアルバイト就業経験のある方を60名以上リクルーティングし、集中して認知課題を行い、偽のフィードバック（絶対評価・相対評価委）、ポジティブ感情、ネガティブ感情、認知課題に対する自己効力感に対する効果を検証した。絶対評価に関しては、参加者の実際のパフォーマンスとは関係なく、高評価群・低評価群に無作為割り付けをした。相対評価群も同様にランダムに高群と低群に無作為割り付けをした。その結果、絶対評価の効果はなく、先行研究と同様に相対評価が低い群のポジティブ感情が下がることが明らかになった。興味深いことに、実際のパフォーマンスと自己効力感に相関がみられないため、自己のパフォーマンスを認識することは難しいと考えられる。このため、仕事の成果が高くても自信につながらないことが考えられる。二つ目の実験では、認知作業の内容を教えずに、ランダムにボタンを押すことでベースラインの得点と反応時間を計測すると教示した群と課題内容を明かさずに自身で課題内容を推測しながら回答する群に無作為割り付けをし、ポジティブ感情、ネガティブ感情、自己効力感を測定した。実験参加者は、実験１と同じ方々であった。予想とは異なり、課題の効果はみられなかった。興味深い点として、実験１において回答者は集中して課題に取り組んだが、実験２では課題内容が明確でないため、集中していない状態であった。そのため、実験１では条件にかかわらずネガティブ感情の低下がみられたが、実験２ではみられなかった。今年度は国際学会や学術論文を視野にしれつつ、これらの実験報告を行う予定である。。

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  • Development of speech communication and its correlates of brain, cognition and motor system: A longitudinal cohort study of typically and atypically developing infants

    Grant number：19H05594  2019.6 - 2024.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (S)  Grant-in-Aid for Scientific Research (S)  Keio University

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    Grant amount： \191490000 （ Direct Cost: \147300000 、 Indirect Cost： \44190000 ）

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  • Research on best dosage forms for deglutition disorders

    Grant number：20K11236  2020.4 - 2023.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)  Grant-in-Aid for Scientific Research (C)  Kyoto Prefectural University of Medicine

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    Grant amount： \4420000 （ Direct Cost: \3400000 、 Indirect Cost： \1020000 ）

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  • Faculty of speech communication and typical and atypical neurocognitive development

    Grant number：19H00632  2019.4 - 2022.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (A)  Grant-in-Aid for Scientific Research (A)  Keio University

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    Grant amount： \45370000 （ Direct Cost: \34900000 、 Indirect Cost： \10470000 ）

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  • Connectome modifying therapy for deglutition disorders

    Grant number：17H02137  2017.4 - 2020.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)  Grant-in-Aid for Scientific Research (B)  Kyoto Prefectural University of Medicine

    YAMAWAKI MASANAGA

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    Grant amount： \13260000 （ Direct Cost: \10200000 、 Indirect Cost： \3060000 ）

    In this study, we clarified the effects of aging and food content on the network between swallowing centers, and obtained data that were the basis for the development of a new treatment method for swallowing movement by modifying the cerebral-medullary network. The scope of the research is to establish scientific evidence for clinical application and prepare for clinical application, and we plan to continue the research separately for subsequent clinical trials.
    As a direct result of this study, a new therapeutic basis for dysphagia, which currently has only symptomatic treatment, was obtained. The device used in this study can be used at bedside or at home, and is expected to be widely used clinically in the medical field in the future.

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  • fNIRS脳機能計測に基づく虐待判定のための新たな客観的指標の創生

    Grant number：17K01915  2017.4 - 2020.3

    日本学術振興会  科学研究費助成事業 基盤研究(C)  基盤研究(C)  中央大学

    水島 栄, 檀 一平太

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    Grant amount： \4680000 （ Direct Cost: \3600000 、 Indirect Cost： \1080000 ）

    現在、社会問題となっている児童虐待。臨床現場では子ども本人からの聞き取り等を中心に処遇判定を行っており、未だ客観的なエビデンスに基づいた虐待判定は実現されていない。
    本研究は、虐待判定の客観的エビデンスを反映した複合評価モデルを、脳機能計測・唾液ホルモン測定・心理評価を用いて構築する。これを実現するためにはADHD児の臨床像と被虐待児の臨床像が類似しているという医療現場での課題を解決する必要がある。被虐待児の多くは、潜在的に発達障害を持っている可能性があり、ADHD(注意欠如多動症)児に臨床像が酷似している。そのため、両者の鑑別は非常に難しい。そのためにADHD児と定型発達児の判別を8割で可能にしたfNIRS (functional near-infrared spectroscopy)による判別法をADHD児と被虐待児に応用し、虐待評価の客観的指標の構築を目指す。
    平成30年度は、積極的に研究協力者（被験者）に対してfNIRSを用いた脳機能計測データおよび、唾液中ホルモン計測、更に「こころファイル」として統合された心理尺度バッテリー評価の蓄積と解析を行った。
    定型発達児に関しては、中央大学理工学部に新たに生体臨床研究室を設置し、静かな環境下、知能検査及び唾液採取等を行った。ADHD児、及び被虐待児を含む不適切な養育を経験している臨床的に介入が必要な児童群は、獨協医科大学埼玉医療センター子どものこころ診療センターでリクルートを、行いデータを収集した。
    唾液中ホルモン解析に関しては、獨協医科大学埼玉医療センターの共同研究室において解析を行った。平成30年度に目標とした被験者獲得数まで達成できなかったが、定型発達児及び、臨床群のリクルートは順調に進んでおり、31年度も引き続き研究を継続していく。

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  • Resilience model of PTG to improve QoL following a disaster

    Grant number：17K12622  2017.4 - 2020.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)  Chuo University

    Kyutoku Yasushi

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    Grant amount： \4030000 （ Direct Cost: \3100000 、 Indirect Cost： \930000 ）

    Based on the model that the researchers in this project, we aimed to enhance quality of life (QoL) through improvements in Posttraumatic growth (PTG) following the potentially traumtic event (PTE). In 2017 and 2018, we found the existence of illusory PTG group by examining PTG trajectory patterns. In 2019, we also found that illusory PTG menbership is associated with lowered state of QoL. In 2020, we published the findings above in Journal of Traumatic Stress. Finally, we developed a method to predict illusory PTG trajectory membership. These findings contributed to find out existence of multiple PTG trajectory patterns and its relationship with QoL. Also, the findings suggested the importance of eraly intervention.

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  • ADHD児行動特性の個性表出を目指したfNIRS脳機能検査の早期適用化

    Grant number：17H05959  2017.4 - 2019.3

    日本学術振興会  科学研究費助成事業 新学術領域研究(研究領域提案型)  新学術領域研究(研究領域提案型)  中央大学

    檀 一平太

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    Grant amount： \4940000 （ Direct Cost: \3800000 、 Indirect Cost： \1140000 ）

    本研究は、「右前頭前野の脳活動をバイオマーカーとしたfNIRSによるADHD診断法の開発」というシーズ研究を発展させて展開した。ADHDの中核症状である抑制機 能を計測するために、これまではGo/Nogo課題を用いていたが、これらは６歳以上の就学児におけるfNIRS脳機能画像解析用に最適化されたものであった。一方 で、６歳未満の未就学児での実行には最適化されていなかった。現行課題の検討を詳細におこなったところ、課題の遂行時間を短くすることによって、より効率的に脳機能を評価できることがわかり、就学前の遂行可能性が高まった。一方で、ADHD児の病態によって、脳活動のパターンが異なる可能性も探索的に検討した。この結果、ADHD児においてASD（自閉症スペクトラム症）の併存によって脳活動のパターンが異なることが明らかとなった。ADHD単独発症型の場合、Go/Nogo課題遂行時に右前頭前野の賦活は低下しているが、メチルフェニデート徐放剤投薬によって賦活が上がることが分かった。一方で、ASD併存型の場合、Go/Nogo課題遂行時に右前頭前野の過活動があり、メチルフェニデート徐放剤投薬によって賦活が収まることが分かった。同じADHD児であっても、ADHD単独発症型とASD併存型では、性格や行動特性は異なるが、抑制機能の遂行や薬物応答の面でも脳活動パターンが異なる異なることが明らかになった。さらに、右前頭前野に加え、頭頂葉の活動パターンを考慮することによって、ADHD単独発症型とASD併存型の判別が個人レベルでも高い精度で行えることがわかった。これらの研究によって、ADHD児において、個性の一翼を担う個人特性と脳内表象の可視化が実現できたと考えられる。

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  • Typical and atypical development of cerebral substrates engaging in language and social cognition

    Grant number：15H01691  2015.4 - 2019.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (A)  Grant-in-Aid for Scientific Research (A)  Keio University

    MINAGAWA Yasuyo, ARIMITSU Takeshi, KUMAZAKI Hirokazu

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    Grant amount： \42900000 （ Direct Cost: \33000000 、 Indirect Cost： \9900000 ）

    The present study aimed to reveal typical and atypical development of language and social cognitive abilities and their correlates of cerebral substrates in human infants. Further, we tried to extract early marker of developmental disabilities such as autistic spectrum disorders (ASD) by correlating early neural and behavioral markers and later general development. To this end, we examined typically developing infants (TD) and infants-at-risk for ASD longitudinally from their age of 3 months-old to 3-years-old. One of our aims of the study was to construct a cohort of infant-at-risk and we successfully recruited about 80 infants for our cohort who participated in our longitudinal experiments. The results showed various group differences in brain connectivity and responses and eye movement between TD and ASD groups. Furthermore, we found some candidates of early behavioral markers for developmental disabilities which involve fine-motor movements and responsiveness to social cues.

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  • Development of dysphagia rehabilitation besaed on automatic imitation

    Grant number：15K01380  2015.4 - 2018.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)  Grant-in-Aid for Scientific Research (C)  Kyoto Prefectural University of Medicine

    Matsuda Goh

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    Grant amount： \4680000 （ Direct Cost: \3600000 、 Indirect Cost： \1080000 ）

    We investigated whether one's own swallowing may be aided by seeing or hearing other people swallow. Humans have a tendency to unconsciously imitate the actions of other individuals, which is known as automatic imitation. If automatic imitation of swallowing can be achieved, it would lead to the development of a simple and intuitive rehabilitation method for patients with dysphagia. We performed three experiments. Two behavioral experiments indicated that automatic imitation of swallowing was elicited when the swallowing sound was heard, rather than when a swallowing motion was seen. A brain imaging study suggested the left inferior frontal gyrus and the right superior temporal gyrus were involved in automatic imitation elicited by the sound of swallowing.

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  • Development and evolution in morphogenesis of human brain and skull

    Grant number：15K12619  2015.4 - 2018.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research  Grant-in-Aid for Challenging Exploratory Research  The University of Tokyo

    Taga Gentaro, HOMAE Fumitaka, TSUZUKI Daisuke

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    Grant amount： \3770000 （ Direct Cost: \2900000 、 Indirect Cost： \870000 ）

    Landmark points of the brain and cranial morphology were extracted using magnetic resonance imaging (MRI) of the head of 16 human infants and children from 3 to 22 months old, and the changes in size and morphology during development were analyzed. The study revealed that (1) there is a large morphological variation in a specific region of the brain, (2) the skull grows anisotropically in the anterior-posterior and lateral directions, and (3) the relative positional relationship between the brain and the skull landmark points is stable, in the course of development. The possibility that the diversity of brain and skull morphology in development leads to the evolution of the brain was discussed.

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  • Modeling the psychological adjustment to the 2011 Tohoku Earthquake and Tsunami

    Grant number：26510018  2014.4 - 2018.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)  Grant-in-Aid for Scientific Research (C)  Chuo University

    Kyutoku Yasushi, WATANABE Eiju

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    Grant amount： \4550000 （ Direct Cost: \3500000 、 Indirect Cost： \1050000 ）

    A huge complex disaster such as 2011 Tohoku Earthquake and Tsunami evokes large stress among victims. Well known psychological reactions include posttraumatic stress (PTS) and posttraumatic growth (PTG). In the current study, we examined the following three research topics using online questionnaire. First, the current longitudinal study replicated the psychological adjustment model established in seeds study where cross-sectional design was used. Second, we identified the PTS vulnerable group and its correlated variable such as daily dysfunction prolonged more than three months. Finally, we found that different pattern of relationship between PTS and PTG would be captured depending on duration between the measurements.

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  • Color and Musical Sense integration: Cerebral Science of Brain Science and Visual Look Design

    Grant number：26350016  2014.4 - 2017.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)  The University of Aizu

    ASAI NOBUYOSHI, Keitaro Naruse, Kurumisawa Jun, Ippeita Dan

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    Grant amount： \4680000 （ Direct Cost: \3600000 、 Indirect Cost： \1080000 ）

    We referee to the phrase “synesthesia in art” as a variety of cross-modal arts that use the co-operation of the senses, for example, seeing and hearing.
    The first work is in the sonata form and the key varies F, C, F, Bb, F major in order. The synesthetic colors are strongly dominant in the start (fade-in), and increased at the change of keys, and drop off quickly. The colors are also strongly associated with movements of the animation characters. For example, as the pony Pegasus flies the colors increase and as he/she falls the colors decrease. The techniques shown in Fantasia may reveal the relation between “synesthesia in art” and “neurological synesthesia,” and the impact of Fantasia over the recent animation films and music videos.

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  • A novel therapeutic approach for dysphagia affecting with CNS connectome

    Grant number：26350578  2014.4 - 2017.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)  Grant-in-Aid for Scientific Research (C)  Kyoto Prefectural University of Medicine

    Yamawaki Masanaga

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    Grant amount： \4550000 （ Direct Cost: \3500000 、 Indirect Cost： \1050000 ）

    The swallowing performance is influenced by various conditions. There are subcortical and cortical centers above the brainstem that induced swallowing movement, however, their specific role and connections are not well understood from the viewpoint of postural change. We applied functional near-infrared spectroscopy (fNIRS), an optical method that non-invasively measure cortical hemodynamics, for brain mapping in swallowing with postural change.The haemodynamic pattern during swallowing appeared different in sitting versus in supine position in BA 6 and BA 40. Our findings suggest that the sensory input is more important in deglutition. We targeted therapeutic points by mapping functional connectivity on swallowing movements.

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  • A damage estimation model applying a damage boundary curve and considering the purchasing behaviour of consumers

    Grant number：26850160  2014.4 - 2017.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B)  Grant-in-Aid for Young Scientists (B)  National Agriculture and Food Research Organization

    Kitazawa Hiroaki, KYUTOKU Yasushi, DAN Ippeita

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    Grant amount： \4030000 （ Direct Cost: \3100000 、 Indirect Cost： \930000 ）

    It is difficult to define damage to fresh produce compared to damage to industrial products. We consider the purchasing behaviour of consumers, such as whether they would like to purchase a fresh produce product, in defining damage to fresh produce. Thus, this study, which uses apples as the fresh product, surveyed the relationship between the damaged areas resulting from several shock conditions and the price that consumers thought reasonable. The results showed that the price that the consumers judged to be reasonable did not change markedly even if the damage area increased to a certain degree. This finding contributes to optimizing cushioning packaging and/or to establishing a reasonable price for fresh produce.

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  • Diffuse optical tomography meeting probablistic registration

    Grant number：25282243  2013.4 - 2016.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)  Grant-in-Aid for Scientific Research (B)  Chuo University

    Dan Ippeita

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    Grant amount： \18200000 （ Direct Cost: \14000000 、 Indirect Cost： \4200000 ）

    In the past two decades, two-dimensional version of fNIRS has acquired various applications, and has developed to be a three-dimensional imaging technique called diffuse optical tomography (DOT), in which illuminator-detector pairs were formed at various distances in an overlapping ways to reconstruct depth-resolved image. Prerequisite for high-resolution image of DOT is the corresponding subject-specific image of brain and head tissue structures, which are not always available. Thus, we developed the probabilistic version of the atlas-guided DOT and examine its feasibility as an MRI-free approach to anatomically guided DOT image reconstruction. The cost of not using subjects’ own MRIs was reasonablly small. Moreover, we adopted a new method referring to Eigen values to effectively control multiplicity in multi-channel fNIRS using effective multiplicity derived from the eigenvalues of correlation matrices, with Meff being controlled at 10 to 15 in a 44-channel setting.

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  • Brain atlas of the miniature pig to establish new animal model for image-assisted stereotaxic surgery.

    Grant number：24500480  2012.4 - 2016.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)  Grant-in-Aid for Scientific Research (C)  Kyoto Sangyo University

    SAITO Toshiyuki, WATANABE Eiju, SASAKI Sei-ichi, DAN Ippeita, OGURO Keiji, YOKOTA Hidenori, UGA Minako

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    Grant amount： \5460000 （ Direct Cost: \4200000 、 Indirect Cost： \1260000 ）

    There are quite limited experimental large animals for use in preclinical brain research. In this study, we aimed to make the brain atlas of the miniature pigs for promoting the preclinical research. Mexican hairless pig has been used. In the brain of this animal, we examined to get images with the common standard planes by Magnetic Resonance (MR) measurement and those of the serial brain sections. There have been observed the intracerebral markers to set the common horizontal standard plane, anterior and posterior commissure. These markers were identified by the MR imaging and by Nissl staining of the brain sections. Besides, we put glass-markers visualized by MRI to adjust the common vertical standard planes in both the MR images and the brain sections. Technically, the common standards planes are able to be set in both the MR images and the brain sections, thereby partially making a draft of the integrated brain atlas using Mexican hairless pig.

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  • The development of the functional Near-infrared Cortical Imaging (fNCI).

    Grant number：25670625  2013.4 - 2015.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research  Grant-in-Aid for Challenging Exploratory Research  Jichi Medical University

    UGA Minako, WATANABE Eiju, DAN Ippeita, SAITO Toshiyuki

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    Grant amount： \3770000 （ Direct Cost: \2900000 、 Indirect Cost： \870000 ）

    Functional near-infrared spectroscopy (fNIRS) is a non-invasive imaging technique of the human brain hemodynamics. However, direct cortical measurement using fNIRS has yet to be realized.
    We developed functional Near-infrared Cortical Imaging (fNCI), which enables the measurement of cortical hemodynamics directly from the brain surface with higher spatial resolution. We validated the fNCI system using miniature pigs. fNCI successfully detected the somatotopy of pig nostril sensation, as assessed in comparison with concurrent and sequential SEP measurements on the same stimulation sites.
    Our new technique can measure the cerebral activities directly from the cortical surface with higher spatial resolution than that of the transcranial fNIRS. This study provides a clue for investigating the theoretical and technical principles of NIRS and possible application of our technique for direct cerebral blood flow monitoring during the human brain surgery.

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  • Development of communication brain: Functional connectivity

    Grant number：24300105  2012.4 - 2015.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)  Grant-in-Aid for Scientific Research (B)  Keio University

    MINAGAWA Yasuyo, YAMAMOTO Jun-ichi, DAN Ippeita, ARIMITSU Takeshi, YAGIHASHI Tatsuhiko

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    Grant amount： \17940000 （ Direct Cost: \13800000 、 Indirect Cost： \4140000 ）

    The present study investigated whether and how functional cerebral activity and connectivity in the early developmental stage relate to later language and social development. For this purpose, we performed a longitudinal study for typically developing infants, preterm infants and infants-at-risk at their age between 0 to 3 years-old to collect both behavioral and neurophysiological data. The results revealed that cerebral response to phonemic contrast can predict later language development particularly language production. Furthermore, our experiment using maternal vs. stranger’s speech indicated that exclusively for term infants, functional connectivities during listening to maternal speech were strengthened in the language brain areas and anterior superior temporal gyrus on the right side which is associated with social voice identification. These results suggest that cerebral activity in the early development can be a suitable predictor for later language and social development.

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  • The development of the extended normalized brain data, which includes reference points on the skull.

    Grant number：24659656  2012.4 - 2015.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research  Grant-in-Aid for Challenging Exploratory Research  Jichi Medical University

    WATANABE Eiju, UGA Minako, DAN Ippeita

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    Grant amount： \3640000 （ Direct Cost: \2800000 、 Indirect Cost： \840000 ）

    The pig is increasingly used in neuroscience research because of the advantages of pig brain compared to that of rodents. The pig brain is more gyrencephalic than rodent brain and is large enough for neurosurgery or imaging techniques. However, the basic information about miniature pig for the brain research is not established yet.
    We tried to make the extended normalized brain data of miniature pig, which contained the brain data and the skull data around the brain. We took the CT and MRI of six Mexican hairless pigs’ heads, and established the fusion protocol of CT and MRI data using new marker. In order to make normalized data, we need to set reference points on the brain and the skull. From CT data, we selected 6 constant points from 21 candidates on the skull surface as the reference points for the transformation. The reference points of the brain are now under investigation. After the brain reference points are decided, the normalized data can be made by our protocols.

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  • Neuroimaging study for exploring remaining cortical function of aphasic patients

    Grant number：23390354  2011.4 - 2014.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)  Grant-in-Aid for Scientific Research (B)  Jichi Medical University

    WATANABE Eiju, DAN Ippeita

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    Grant amount： \18720000 （ Direct Cost: \14400000 、 Indirect Cost： \4320000 ）

    The current study explored the remaining cortical function of aphasic patients using functional neuroimaging technique exemplified as optical topography. Among two major language tasks, namely, naming and verbal fluency tasks, which have seemed suitable for this purpose, we verified that the naming task had clearer laterality with large enough signal amplitudes. Optical topography analyses on aphasic patients at sub-acute phase revealed that activation of the left Wernicke area might be a typical neural signature to represent compensational cortical activation for the dysfunction of the Broca area.

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  • 質感言語表現における多感覚相互作用：ＭＥＧによる脳内表象の解析

    Grant number：23135526  2011.4 - 2013.3

    日本学術振興会  科学研究費助成事業 新学術領域研究(研究領域提案型)  新学術領域研究(研究領域提案型)  自治医科大学

    檀 一平太

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    Grant amount： \10010000 （ Direct Cost: \7700000 、 Indirect Cost： \2310000 ）

    本研究の目的は、質感の言語表現の脳内表象を多感覚相互作用の観点から明らかにすることである。このため、オノマトペ（擬音・擬態語）の脳内表象を、MEG（脳磁計）によって解析した。
    刺激として、日本語の語彙全体を母集団とし、ABAB型のオノマトペを探索し、７４語の候補語を選択した。次に、ABAB型オノマトペ（がくがく等）に相当するABCD型の意味語（がくそつ等）、発音特性を近似させたABABオノマトペ様無意味語（ばぷばぷ等）とABCD型無意味語（ばぷとく等）を生成した。これらについて、モーラ長を一定にし、実験刺激を作成した。７４語×４＝２９６語を１セットとし、セット内で刺激提示順序をランダム化し、約５秒に１回の音声刺激提示を実施し、MEGを用いて脳神経応答の時系列活動パターンを計測した。実験は４セットを繰り返した。被験者は１３人とし、音声刺激提示時を基準とし、聴覚事象関連磁場を解析した。
    解析には、課題の平均正答率が60%を上回る被験者のみ（9名）を採用した。ソース解析はMinimum norm estimationを用い、脳表750点の電流密度を推定した。さらに関心領野を設定し、各領野での合成電流密度波形を生成した。解析では第三モーラの490msの活動に着目し、信号源の強度を２要因（品詞／意味）の分散分析を用いて解析した。
    右縁上回、右角回、右側頭葉後部における被験者間合成電流密度のオノマトペ有意味語-名詞有意味語間の比較において、第三モーラに付随した電流密度の有意な増加を確認した。これはABAB型オノマトペの第三モーラをトリガーに音韻・意味処理が加速している可能性を示唆している。また、角回において、品詞と意味の交互作用が認められた。これは、同定されたオノマトペにおいて特異的な脳応答は、音韻・意味処理におけるオノマトペ特有な認知処理メカニズムによる特性であることを示唆している。

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  • A New Therapeutic Strategy for Dysphagia: Modification of Deglutition Center in Cerebrum and Pons

    Grant number：23500580  2011 - 2013

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)  Grant-in-Aid for Scientific Research (C)  Kyoto Prefectural University of Medicine

    YAMAWAKI Masanaga, DAN Ippeita

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    Grant amount： \4940000 （ Direct Cost: \3800000 、 Indirect Cost： \1140000 ）

    There are subcortical and cortical centers above the brainstem that induce swallowing movement, however, their specific role and connections are not well understood. We applied functional near infrared spectroscopy (fNIRS) for brain mapping in swallowing and swallow related movements. Twenty five of volunteers and seven patients with dysphagia were examined by fNIRS. Subjects sitting on the chair were put 34 channel holder of OMM 2000 (Shimadzu, Kyoto, Japan). BA 4, BA 3,1,2, BA 6 were activated both in command and noncommand swallow in our study. The haemodynamic pattern during swallowing appeared different in command versus noncommand tasks in BA 6 and BA 40. Our findings suggest that the sensory input is more important in noncommand than in command swallow. These data show that cortical process to initiate swallowing movements is altered by the triggers.

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  • Exploring quantitative association between neural and hemodynamic responses using MEG-NIRS simultaneous measurement

    Grant number：23650217  2011 - 2012

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research  Grant-in-Aid for Challenging Exploratory Research  Jichi Medical University

    DAN Ippeita

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    Grant amount： \3510000 （ Direct Cost: \2700000 、 Indirect Cost： \810000 ）

    We introduced adaptive methods to find the optimal HRF for temporal analysis of NIRS data. Application of the GLM with regression to a temporally optimized HRF on the functional activation data during different language tasks revealed

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  • Neurocognitive investigation of syntactic processing on school-aged children: A cross-sectional study

    Grant number：22242012  2010 - 2012

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (A)  Grant-in-Aid for Scientific Research (A)  Tokyo Metropolitan University

    HAGIWARA Hiroko, DAN Ippeita, HOSHINO Takahiro, SUGIURA Lisa, HOMAE Fumitaka, HATA Masahiro, YARIMIZU Hidekazu, MATSUBA Hiroko

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    Grant amount： \48230000 （ Direct Cost: \37100000 、 Indirect Cost： \11130000 ）

    By using simultaneous functional near-infrared spectroscopy (NIRS) and event-related potentials (ERPs), we investigated the stages of L2 syntactic processing in Japanese elementary school children who learn English at school. In the processing of sentences with word order violations, increased bilateral cortical activation was found in the high proficiency group with more left lateralization compared to the low proficiency group. The positive ERP component was also observed in the high proficiency group. These results suggest that children are gradually acquiring the ability to recognize L2 grammatical rules (phrase structure rules) by learning them in the foreign language context.

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  • A New Therapeutic Approach for Dysphagia : Modification of Deglutition Center in Cerebrum and Pons

    Grant number：20500440  2008 - 2010

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)  Grant-in-Aid for Scientific Research (C)  Tokyo Medical and Dental University

    YAMAWAKI Masanaga, DAN Ippeita

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    Grant amount： \4550000 （ Direct Cost: \3500000 、 Indirect Cost： \1050000 ）

    There are subcortical and cortical centers above the brainstem that induce swallowing movement, however, their specific role and connections are not well understood.We applied functional near-infrared spectroscopy (fNIRS) for brain mapping in swallowing and swallow-related movements Twenty-five of volunteers were examined by fNIRS. Subjects sitting on the chair were put 34-channel holder of OMM-2000 (Shimadzu, Kyoto, Japan). Sensorimotor cortex and frontal lobe were set as the region of the interest. We performed, 1) blocked motor tasks (hand grip, tongue protrusion), 2) event-related tasks (command or non-command swallow). The statistical method used was a general linear model employing a two-level summary statistics approach for random effects analysis with a one-tailed t test. Activation areas in each blocked task were detected separately in SMI (p < o.o5 by Student t, one-tailed, FDR controlled). During bolus swallowing, activation was detected in tongue SMI and BA 6 (p < o.o5, one-tailed, FDR controlled). The haemodynamic pattern observed during swallowing was different during the command versus non-command tasks in BA 6 and BA 40 (p < o.o5, two-tailed, not corrected). In accordance with prior reports, BA 4, BA 3,1,2, BA 6 were activated both in command and non-command swallow in our study. The haemodynamic pattern during swallowing appeared different in command versus non-command tasks in BA 6 and BA 40. Our findings suggest that the sensory input is more important in non-commandthan in command swallow. These data show that cortical process to initiate swallowingmovements is altered by the triggers.

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  • NIRS研究のための頑健性のあるリサンプリング統計解析法の開発

    Grant number：19650079  2007 - 2008

    日本学術振興会  科学研究費助成事業 萌芽研究  萌芽研究  独立行政法人農業技術研究機構

    檀 一平太

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    Grant amount： \2900000 （ Direct Cost: \2900000 ）

    NIRS(近赤外分光分析法)は脳機能イメージング法として普及が進みつつあるが、統計的なデータ解析法の開発は遅れている。これまで、fMRI(機能的核磁気共鳴撮像法)に用いられていた母数的な統計解析を流用する試みはあったが、比較的均一なばらつきを持つfMRIデータには適するものの、ばらつきの不均一なNIRSデータの解析には、非母数的なリサンプリング法が最適である可能性が高い。そこで、本研究では、NIRSのデータ解析における種々の問題、すなわち、計測部位、被験者間のデータのばらつき、乳幼児計測において頻発する欠損データなどを、リサンプリング法を用いた、頑健な統計手法の適用によって解決することを目的とした。脳機能イメージング研究で通常用いられるリサンプリング法としては、パーミューテーション法が挙げられるが、この方法は母集団の正規性や等分散性は仮定しないものの、交換可能性という前提の下に成立する方法である。NIRSの場合、データの均質性はfMRIよりも低く、交換可能性が保証されるとは限らない。そこで、パーミューテーション法の中でも最も前提条件の緩い非交換ブートストラップ法の適用を試みた。さらに、多チャンネル計測における多重比較問題を解決するため、脳機能イメージング研究としては始めて、ステップダウンMaxT補正の適用を試みた。これらの手法を舌運動課題、言語想起課題遂行時のNIRSデータに適用したところ、非交換ブートストラップ法とステップダウンMaxT補正の組み合わせは母数的方法とボンフェローニ多重比較補正の組み合わせよりも検出力が高いことが判明した。また、パーミューテション法と比較しても、遜色のない検出力を有することを示した。非交換ブートストラップ法は欠損値のあるデータにも有効な方法であり、NIRS計測に極めて有用な手法として今後の適用が期待できる

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  • Study on the neural mechanism that supports the functional recovery of aphasia by using optical topography.

    Grant number：18390404  2006 - 2008

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)  Grant-in-Aid for Scientific Research (B)  Jichi Medical University

    WATANABE Eiju, DAN Ippeita

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    Grant amount： \17040000 （ Direct Cost: \14400000 、 Indirect Cost： \2640000 ）

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  • 小型近赤外線計測装置の開発による動物脳機能の測定

    Grant number：18653081  2006 - 2007

    日本学術振興会  科学研究費助成事業 萌芽研究  萌芽研究  慶應義塾大学

    渡辺 茂, 檀 一平太

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    Grant amount： \3300000 （ Direct Cost: \3300000 ）

    1)小型LEDによる動物用NIRSの試作本年度も引き続き小型LEDを頭蓋に固定して近赤外光を照射し、やはり頭蓋に受光部も固定して、動物側で、光学シグナルを電気信号に変えて計測器に送る実験を行った。その反射光の測定を行った。これまでにハトを実験動物とした場合には瞬目反射による光学的ノイズが大きいことがわかっているので、ラットを実験動物とした。その結果、反射光の測定はできるが、十分な空間分解能は得られず、近赤外光による能活動部位の同定は困難であることがわかった。さらに、どの程度の近赤外光の散乱があるかを調べるために赤外線ビデオカメラを用いて検討を行った。その結果、近赤外光は脳全体に拡散しており、測定した反射光は脳全体の積分値であることがわかった。そこで、近赤外光のパワーを下げることを試みたが、全体への拡散を減ずることはできなかった。さらにLEDと頭蓋の間に微小な光学系を組み込み、光軸を絞ることを模索したが、動物の頭蓋に固定することを考えると実際的でないことがわかった。
    2)近赤外光による脳全体の画像解析の可能性近赤外光が脳全体に拡散することから、逆に2方向に赤外線ビデオカメラを設置し、脳全体の画像を測定してより近赤外光を吸収する部位とそうでない部位を特定することが可能ではないかという発想を得た。ソフトウエアの面と実際の実験可能性の両面から検討した結果、ソフト的にはなんとか可能であろうという結論を得た。しかし,実際の実験遂行上はどうしても動物の頭部を固定する必要があり、固定による光の遮蔽が生じ、また、本来の目的である自由運動中の動物の脳活動の測定には不適切であることがわかった。
    以上、研究の過程で多くの知見が得られたが、行動中の動物の脳活動測定法としてのNIRSは現時点では実現できないことがわかった。

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  • 遺伝子検索と超高感度イメージングによる大脳神経回路網形成における分子機構の解析

    Grant number：96J04668  1998 　 　

    日本学術振興会  科学研究費助成事業 特別研究員奨励費  特別研究員奨励費  東京大学

    檀 一平太

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    Grant amount： \900000 （ Direct Cost: \900000 ）

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  • 脳機能イメージング、サイコメトリクスによるヒト認知構造の可視化および方法論開発

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    Grant type：Competitive

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Other

  • 資格等

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    学校心理士（2022年1月）
    臨床発達心理士（2023年4月）
    全日本スキー連盟２級（2025年1月）

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